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经皮穿刺房间隔缺损封堵器微创姑息治疗恶性气管食管瘘

Minimally invasive palliative treatment of malignant tracheoesophageal fistula using cardiac septal occluder.

机构信息

Department of Cardiology, Yichang Central People's Hospital, The First College of Clinical Medical Sciences, China Three Gorges University, Yichang, 443003, Hubei, People's Republic of China.

Department of Respiratory, Yichang Central People's Hospital, The First College of Clinical Medical Sciences, China Three Gorges University, NO,183 Yiling Road, Yichang, 443003, Hubei, People's Republic of China.

出版信息

Langenbecks Arch Surg. 2024 Jun 1;409(1):169. doi: 10.1007/s00423-024-03363-3.

Abstract

INTRODUCTION

Tracheoesophageal fistula (TEF) especially malignant TEF (mTEF) is an uncommon yet critical medical condition necessitating immediate intervention. This life-threatening condition frequently manifests in critically ill patients who are dependent on prolonged mechanical ventilation and are unsuitable candidates for thoracotomy due to their compromised health status. The Management of these mTEF patients remain a significant challenge.This study aimed to evaluate the safety and efficacy of using a cardiac septal occluder for the closure of mTEF.

METHODS

8 patients with mTEF underwent closure surgery using atrial/ventricular septal defect (ASD/VSD) septal occluders at the Respiratory Department of HuBei Yichang Central People's Hospital from 2021 to 2023. The procedure involved percutaneous placement of the occluder through the fistula to achieve closure.

RESULTS

The placement of the cardiac septal occluder was successfully achieved with ease and efficiency in all patients. The study demonstrated that the use of cardiac septal occluder therapy in patients with mTEF can alleviate symptoms, improve quality of life, and enhance survival rates, with no significant complications observed. Furthermore, the study provided comprehensive details on surgical indications, preoperative evaluation and diagnosis, selection of occluder, methods of occlusion, and postoperative care.

CONCLUSIONS

The application of cardiac septal occluder in the treatment of mTEF is a safe and effective palliative treatment. This approach may be particularly beneficial for patients with a high risk of complications and mortality associated with traditional surgical interventions.

摘要

介绍

气管食管瘘(TEF),特别是恶性 TEF(mTEF),是一种罕见但严重的医疗状况,需要立即干预。这种危及生命的情况经常发生在依赖长时间机械通气且由于健康状况不佳而不适合开胸手术的重症患者身上。这些 mTEF 患者的治疗仍然是一个重大挑战。本研究旨在评估使用心脏间隔封堵器闭合 mTEF 的安全性和有效性。

方法

2021 年至 2023 年,湖北宜昌中心人民医院呼吸科对 8 例 mTEF 患者采用房间隔/室间隔缺损(ASD/VSD)间隔封堵器进行闭合手术。该手术通过瘘口经皮放置封堵器来实现闭合。

结果

所有患者均成功且轻松地完成了心脏间隔封堵器的放置。研究表明,在 mTEF 患者中使用心脏间隔封堵器治疗可以缓解症状、提高生活质量并提高生存率,且未观察到明显的并发症。此外,该研究还提供了关于手术适应证、术前评估和诊断、封堵器选择、封堵方法以及术后护理的全面详细信息。

结论

心脏间隔封堵器在 mTEF 治疗中的应用是一种安全有效的姑息治疗方法。对于那些因传统手术干预而存在高并发症和死亡率风险的患者,这种方法可能特别有益。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf64/11144155/10a96a3ac02c/423_2024_3363_Fig1_HTML.jpg

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