探讨感染因子与自身免疫性疾病的关系：综述。
Exploring the relationship between infectious agents and autoimmune diseases: a review.
机构信息
Laboratory Central, Guangxi Key Laboratory of Metabolic Reprogramming and Intelligent Medical Engineering for Chronic Diseases, Guangxi Health Commission Key Laboratory of Glucose and Lipid Metabolism Disorders, The Second Affiliated Hospital of Guilin Medical University, Guilin, 541199, China.
Department of Neurology, The Second Affiliated Hospital of Guilin Medical University, Guilin, Guangxi, 541199, China.
出版信息
Eur J Clin Microbiol Infect Dis. 2024 Aug;43(8):1505-1516. doi: 10.1007/s10096-024-04869-w. Epub 2024 Jun 3.
The relationship between infectious agents and autoimmune diseases is a complex issue. In recent years, increasing clinical cases have indicated that infectious agents play an important role in the development of autoimmune diseases. Molecular mimicry is currently widely regarded as the primary pathogenic mechanism of various autoimmune diseases in humans. Components of infectious agents can undergo molecular mimicry with components in patients' bodies, leading to the development of various autoimmune diseases. In this article, we provide a brief overview of current research of the current research status on the relationship between infectious agents and autoimmune diseases, and describe our current understanding of their mechanisms of action in order to better understand the pathogenesis, diagnosis, and treatment of autoimmune diseases.
感染因子与自身免疫性疾病之间的关系是一个复杂的问题。近年来，越来越多的临床病例表明，感染因子在自身免疫性疾病的发展中起着重要作用。目前，分子模拟被广泛认为是人类各种自身免疫性疾病的主要发病机制。感染因子的成分可以与患者体内的成分发生分子模拟，从而导致各种自身免疫性疾病的发生。本文简要概述了目前关于感染因子与自身免疫性疾病关系的研究现状，并描述了我们目前对其作用机制的认识，以便更好地了解自身免疫性疾病的发病机制、诊断和治疗。
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