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认知障碍是老年人身体机能下降的一个风险因素。

Cognitive impairment is a risk factor for decreased physical performance in the elderly.

作者信息

Su Dan, Liu Ying, Su Yangling, Zhang Xiaojun, Chan Piu

机构信息

Department of Geriatrics, Liangxiang Hospital of Beijing Fangshan District, Beijing, 102400, China.

Department of Geriatrics, National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital of Capital Medical University, Beijing, 100053, China.

出版信息

Heliyon. 2024 May 28;10(11):e32132. doi: 10.1016/j.heliyon.2024.e32132. eCollection 2024 Jun 15.

Abstract

BACKGROUND

This study aimed to show a 3-year trajectory of physical performance among Chinese elderly in Beijing communities and explore the associations between new adverse events during the 3-year follow-up period and decreased physical performance.

METHODS

A longitudinal observational study included baseline data and transitional information of physical performance from 456 community elders (mean age 67.3 ± 4.9 years, female 43.2 %) at a 3-year follow-up. The Mini-Mental State Examination (MMSE) and the Short Physical Performance Battery (SPPB) were used to measure cognition and physical performance, respectively. The number of chronic diseases, cognitive impairment, malnutrition, depression, knee pain, falls, and frailty were the principal independent variables in multivariate logistic regression analysis.

RESULTS

The proportion of the elderly with poor physical performance (26.97 %) increased to 42.11 % and the proportion of those with good physical performance (44.96 %) dropped to 30.48 % after the three-year follow-up. As for physical performance transitions, 39.47 % of the elderly progressed to a worsening physical status. After adjustment for covariates, only new onset cognitive impairment (OR: 5.17; 95%CI: 2.01-14.54; P = 0.001) was associated with physical performance deterioration.

CONCLUSION

Cognitive impairment is an independent risk factor for decreased physical performance in elderly people. Active interventions targeted at cognitive impairment could help promote healthy aging.

摘要

背景

本研究旨在呈现北京社区中国老年人三年的身体机能轨迹,并探讨三年随访期内新出现的不良事件与身体机能下降之间的关联。

方法

一项纵向观察性研究纳入了456名社区老年人(平均年龄67.3±4.9岁,女性占43.2%)在三年随访期的基线数据和身体机能的过渡信息。分别使用简易精神状态检查表(MMSE)和简短体能测试量表(SPPB)来测量认知和身体机能。慢性病数量、认知障碍、营养不良、抑郁、膝关节疼痛、跌倒和衰弱是多因素逻辑回归分析中的主要自变量。

结果

三年随访后,身体机能较差的老年人比例(26.97%)增至42.11%,身体机能良好的老年人比例(44.96%)降至30.48%。关于身体机能的转变,39.47%的老年人身体状况恶化。在对协变量进行调整后,只有新发认知障碍(比值比:5.17;95%置信区间:2.01 - 14.54;P = 0.001)与身体机能恶化相关。

结论

认知障碍是老年人身体机能下降的独立危险因素。针对认知障碍的积极干预有助于促进健康老龄化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/461b/11168380/0dc62102891c/gr1.jpg

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