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下肢骨折继发隐匿性肺栓塞的早期诊断:18例总结

Early diagnosis of occult pulmonary embolism secondary to lower limb fractures: summary of 18 cases.

作者信息

Di Luqin, Chen Zheng, Wang Xiaoyan, Zhang Jiao, Zhang Jing, Ding Junqin

机构信息

Department of Orthopaedic Surgery, Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, China.

出版信息

Front Med (Lausanne). 2024 May 30;11:1355030. doi: 10.3389/fmed.2024.1355030. eCollection 2024.

Abstract

OBJECTIVES

Pulmonary thromboembolism is a severe but probably underdiagnosed disorder. Patients with lower limb fractures are at high risk for pulmonary thromboembolism. This study aimed to demonstrate the early identification strategies for occult pulmonary thromboembolism.

METHODS

From January to December 2022, 18 patients diagnosed with pulmonary thromboembolism were reviewed for this study. Data on patients' demographics, laboratory test results, and radiographic findings were collected. Finally, the data was analyzed.

RESULTS

Eighteen patients with lower limb fractures were included in this study. All of them present different symptoms, including 12 cases (12/18, 66%) of unexplained decrease in oxygen saturation; 16 patients had deep vein thrombosis in the lower limbs, with nine cases involving proximal veins and seven involving distal veins. One patient had an antithrombin III level of 35%. Thirteen cases were diagnosed with pulmonary embolism using CT pulmonary angiography. Four patients had pulmonary embolisms incidentally detected during coronary CT angiography, and one patient during aortic CT angiography.

CONCLUSION

Patients with lower limb fractures showing chest tightness and unexplained decrease in finger pulse oxygen levels should be assessed for pulmonary thromboembolism. Simultaneously, selecting appropriate diagnostic tools is essential to guaranteeing quick and accurate diagnosis.

摘要

目的

肺血栓栓塞症是一种严重但可能未被充分诊断的疾病。下肢骨折患者发生肺血栓栓塞症的风险很高。本研究旨在证明隐匿性肺血栓栓塞症的早期识别策略。

方法

2022年1月至12月,对18例诊断为肺血栓栓塞症的患者进行回顾性研究。收集患者的人口统计学数据、实验室检查结果和影像学检查结果。最后对数据进行分析。

结果

本研究纳入了18例下肢骨折患者。他们均表现出不同症状,包括12例(12/18,66%)不明原因的血氧饱和度下降;16例患者下肢存在深静脉血栓形成,其中9例累及近端静脉,7例累及远端静脉。1例患者抗凝血酶III水平为35%。13例患者通过CT肺动脉造影诊断为肺栓塞。4例患者在冠状动脉CT血管造影时偶然发现肺栓塞,1例患者在主动脉CT血管造影时发现肺栓塞。

结论

对于出现胸闷且手指脉搏氧水平不明原因下降的下肢骨折患者,应评估其是否存在肺血栓栓塞症。同时,选择合适的诊断工具对于确保快速、准确的诊断至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e92d/11169728/1f6d90c2bab8/fmed-11-1355030-g001.jpg

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