Department of Clinical and Experimental Medicine, University Magna Græcia, 88100 Catanzaro, Italy.
Technical Scientific Association of Food, Nutrition and Dietetics (ASAND), 95128 Catania, Italy.
Nutrients. 2024 May 26;16(11):1629. doi: 10.3390/nu16111629.
Understanding the intricate relationship between nutrition, hormonal balance, and gender-specific factors is crucial for developing targeted interventions to mitigate obesity-related endocrine disruptions and improve metabolic health. This narrative review examines the impact of various dietary patterns on hormonal regulation in both men and women, focusing on their effects on hormonal balance and metabolic health in the context of obesity. Calorie restriction, the Western diet, high-fat diets, low-CHO diets, plant-based diets, and the Mediterranean diet are analyzed in relation to their influence on obesity-related endocrine disruptions and metabolic health. Future research directions include investigating the specific mechanisms underlying dietary influences on hormonal regulation, addressing the gender-specific metabolic differences and body fat distribution, and exploring the dietary needs of individuals undergoing gender transition. Personalized dietary interventions tailored to individual metabolic and hormonal profiles are essential for optimizing health outcomes across the gender spectrum. By integrating gender-specific considerations into dietary recommendations, healthcare professionals can better support individuals in achieving optimal metabolic health and hormonal balance.
理解营养、激素平衡和性别特定因素之间的复杂关系对于制定有针对性的干预措施以减轻肥胖相关的内分泌干扰和改善代谢健康至关重要。本叙述性评论审查了各种饮食模式对男性和女性激素调节的影响,重点关注它们在肥胖背景下对激素平衡和代谢健康的影响。分析了热量限制、西方饮食、高脂肪饮食、低碳水化合物饮食、植物性饮食和地中海饮食对肥胖相关内分泌干扰和代谢健康的影响。未来的研究方向包括研究饮食对激素调节影响的具体机制,解决性别特异性代谢差异和体脂肪分布问题,以及探索正在进行性别转换的个体的饮食需求。针对个体代谢和激素特征量身定制的个性化饮食干预对于优化整个性别范围内的健康结果至关重要。通过将性别特异性考虑因素纳入饮食建议中,医疗保健专业人员可以更好地支持个体实现最佳代谢健康和激素平衡。