Department of Gastroenterology (LIM-35), School of Medicine, University of São Paulo, São Paulo 05508-220, Brazil.
Medical Research Laboratory in Aging (LIM-66), School of Medicine, University of São Paulo, São Paulo 05508-220, Brazil.
Nutrients. 2024 May 31;16(11):1717. doi: 10.3390/nu16111717.
Sarcopenia screening tools have a low capacity to predict adverse outcomes that are consequences of sarcopenia in the elderly population. This study aimed to evaluate the ability of a new sarcopenia screening tool SARC-GLOBAL to predict negative clinical outcomes in the elderly. A total of 395 individuals were evaluated in a 42-month period. The screening tools SARC-GLOBAL, SARC-F, and SARC-CalF and the diagnosis of sarcopenia according to European Working Group on Sarcopenia in Older Persons (EWGSOP2) were performed at the beginning of the study. Logistic and Poisson regression models were applied to assess the predictive value of the tools for the odds and risks of negative clinical outcomes, respectively. The most common negative clinical outcome in the followed population was falls (12.9%), followed by infections (12.4%), hospitalizations (11.8%), fractures (4.3%), and deaths (2.7%). Both SARC-GLOBAL and SARC-F were similar in predicting the odds of falls and hospitalizations during the follow up period, however SARC-CalF only predicted the odds of hospitalizations at 42 months.
肌少症筛查工具预测老年人肌少症不良结局的能力较低。本研究旨在评估一种新的肌少症筛查工具 SARC-GLOBAL 预测老年人负面临床结局的能力。在 42 个月的时间内,共对 395 人进行了评估。在研究开始时,进行了 SARC-GLOBAL、SARC-F 和 SARC-CalF 筛查工具以及根据欧洲老年人肌少症工作组(EWGSOP2)的肌少症诊断。应用逻辑回归和泊松回归模型分别评估工具对负面临床结局的几率和风险的预测价值。在随访人群中最常见的负面临床结局是跌倒(12.9%),其次是感染(12.4%)、住院(11.8%)、骨折(4.3%)和死亡(2.7%)。SARC-GLOBAL 和 SARC-F 在预测随访期间跌倒和住院的几率方面相似,但 SARC-CalF 仅在 42 个月时预测了住院的几率。