直肠癌局部复发高危患者的术中检测
Peroperative detection of patients with rectal cancer at high risk of local recurrence.
作者信息
Silverman S H, Moore J, Thompson H, Keighley M R
出版信息
Ann R Coll Surg Engl. 1985 May;67(3):164-6.
Identification at the time of surgery of patients with rectal carcinoma at high risk of local recurrence may allow a more rational decision to be made regarding the operative procedure to be performed. We have examined tumour bed biopsies and lymph nodes peroperatively using imprint cytology in 20 consecutive patients undergoing radical surgery for rectal carcinoma. The results were checked by subsequent paraffin section histology. We were unable to find lymph nodes in 6 cases (30%) peroperatively. Cytological and histological reporting of the tumour bed biopsies and lymph nodes concurred in 91% and 88% of specimens respectively. Peroperative cytology can differentiate between malignant and benign fixation of rectal tumours, can differentiate between hyperplastic and malignant lymph nodes and may be of value in identifying patients with rectal cancer at high risk of local recurrence.
在手术时识别出具有局部复发高风险的直肠癌患者，可能有助于就拟实施的手术程序做出更合理的决策。我们对20例接受直肠癌根治手术的连续患者术中使用印片细胞学检查肿瘤床活检标本和淋巴结。结果通过随后的石蜡切片组织学检查进行核对。术中我们有6例（30%）未发现淋巴结。肿瘤床活检标本和淋巴结的细胞学和组织学报告分别在91%和88%的标本中一致。术中细胞学检查能够区分直肠肿瘤的恶性和良性固定，能够区分增生性和恶性淋巴结，并且在识别具有局部复发高风险的直肠癌患者方面可能具有价值。
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