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抗糖脂核心免疫球蛋白A抗体检测在非结核分枝杆菌颈面部淋巴结炎诊断中的评估

Evaluation of Anti-Glycopeptidolipid-Core Immunoglobulin A Antibody Detection for the Diagnosis of Nontuberculous Mycobacterial Cervicofacial Lymphadenitis.

作者信息

Willemse Samuel H, Oomens Marjolijn A E M, Karssemakers Luc H E, Lindeboom Jerome A, Schreuder Willem H, Ho Jean-Pierre T F, van der Kuip Martijn, Vlaming Killian E, Kaptein Tanja M, de Lange Jan

机构信息

From the Department of Oral and Maxillofacial Surgery, Amsterdam University Medical Center (UMC) and Academic Centre for Dentistry Amsterdam, University of Amsterdam, Amsterdam, the Netherlands.

Department of Oral and Maxillofacial Surgery, Rijnstate Hospital, Arnhem, the Netherlands.

出版信息

Pediatr Infect Dis J. 2024 Nov 1;43(11):e416-e418. doi: 10.1097/INF.0000000000004462. Epub 2024 Jun 26.

Abstract

A multicenter cross-sectional diagnostic study was carried out including 45 children with nontuberculous mycobacterial cervicofacial lymphadenitis and controls. The tested immunoassay, detecting M. avium- specific anti-glycopeptidolipid-core immunoglobulin A antibodies, had inadequate diagnostic performance in the studied population and seems to be of no additional value in detecting cases of nontuberculous mycobacterial cervicofacial lymphadenitis.

摘要

开展了一项多中心横断面诊断研究,纳入了45例非结核分枝杆菌颈面部淋巴结炎患儿及对照。所检测的免疫测定法用于检测鸟分枝杆菌特异性抗糖脂核心免疫球蛋白A抗体,在研究人群中诊断性能不足,在检测非结核分枝杆菌颈面部淋巴结炎病例方面似乎没有额外价值。

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本文引用的文献

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Development and Evaluation of an NTM-IGRA to Guide Pediatric Lymphadenitis Diagnosis.
Pediatr Infect Dis J. 2024 Mar 1;43(3):278-285. doi: 10.1097/INF.0000000000004211. Epub 2023 Dec 18.
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Long-Term Esthetic Outcome of Different Treatment Modalities for Nontuberculous Mycobacterial Cervicofacial Lymphadenitis.
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