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关于石墨烯在疫苗设计中潜在应用前景的叙述性综述:评估碳纳米片在纳米疫苗生产中的利弊

A Narrative Review on the Promising Potential of Graphene in Vaccine Design: Evaluating the Benefits and Drawbacks of Carbon Nanoplates in Nanovaccine Production.

作者信息

Zare-Zardini Hadi, Saberian Elham, Jenča Andrej, Jenča Andrej, Petrášová Adriána, Jenčová Janka

机构信息

Department of Biomedical Engineering, Meybod University, Meybod 89616-99557, Iran.

Klinika and Akadémia Košice Bacikova, Pavol Jozef Šafárik University, 040 01 Kosice, Slovakia.

出版信息

Vaccines (Basel). 2024 Jun 14;12(6):660. doi: 10.3390/vaccines12060660.

Abstract

Graphene, a two-dimensional material consisting of a single layer of carbon atoms arranged in a honeycomb lattice, has shown great potential in various fields, including biomedicine. When it comes to vaccine development, graphene can offer several advantages due to its unique properties. Potential applications of graphene in vaccine development include improved vaccine delivery, adjuvant properties, improved vaccine stability, improved immune response, and biosensing capabilities. Although graphene offers many potential benefits in vaccine development, there are also some drawbacks and challenges associated with its use. Although graphene shows promising potential for vaccine development, overcoming the challenges and limitations associated with its use is critical to realizing its full potential in the field of immunization. Further research and development efforts are needed to overcome these drawbacks and take advantage of graphene for improved vaccine formulations. In this review, we focus on the advantages and disadvantages of graphene for vaccine development.

摘要

石墨烯是一种由单层碳原子排列成蜂窝晶格的二维材料,在包括生物医学在内的各个领域都显示出了巨大潜力。在疫苗研发方面,由于其独特性质,石墨烯能带来诸多优势。石墨烯在疫苗研发中的潜在应用包括改善疫苗递送、具备佐剂特性、提高疫苗稳定性、增强免疫反应以及具备生物传感能力。尽管石墨烯在疫苗研发中具有诸多潜在益处,但使用它也存在一些缺点和挑战。虽然石墨烯在疫苗研发中展现出了有前景的潜力,但克服与其使用相关的挑战和限制对于在免疫领域实现其全部潜力至关重要。需要进一步的研发努力来克服这些缺点,并利用石墨烯改进疫苗配方。在本综述中,我们聚焦于石墨烯在疫苗研发中的优缺点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b4e1/11209486/e1a1b40b8b6d/vaccines-12-00660-g001.jpg

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