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以肩胛骨肿块为表现的转移性子宫内膜癌:一例报告及文献复习

Metastatic endometrial carcinoma presenting as a scapular mass: A case report and literature review.

作者信息

Rahestyningtyas Eccita, Saraswati Wita

机构信息

Department of Obstetrics & Gynecology, Faculty of Medicine, Universitas Airlangga/ Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.

出版信息

Case Rep Womens Health. 2024 Jun 8;42:e00628. doi: 10.1016/j.crwh.2024.e00628. eCollection 2024 Jun.

Abstract

Bone metastases of endometrial cancers are quite rare, especially in the scapula. Only two previous reports of such cases were found in the literature, and in each case a different approach to diagnosis was used. There are no established recommendations for screening for bone metastases at diagnosis or after initial treatment of endometrial cancers. In the present case, a 55-year-old woman with progressive abdominal distension was diagnosed with a cystic mass. Histopathological analysis revealed grade II synchronous endometrioid carcinoma in both the endometrium and the ovaries. The patient received three cycles of combined paclitaxel and carboplatin chemotherapy. Seven months after the last chemotherapy cycle, a palpable lump was found in the right shoulder, suggesting a lesion in the right scapula. A bone scan revealed heightened radioactivity uptake, highlighting the unpredictable nature of the disease progression. The choice of diagnostic imaging modality remains challenging. This case emphasises the need for ongoing investigation of the mechanisms of distant metastasis and for the development of standardised diagnostic and therapeutic strategies.

摘要

子宫内膜癌的骨转移相当罕见,尤其是发生在肩胛骨的情况。文献中仅发现两例此类病例报告,且每例采用了不同的诊断方法。对于子宫内膜癌诊断时或初始治疗后骨转移的筛查,尚无既定的推荐方案。在本病例中,一名55岁进行性腹胀的女性被诊断为囊性肿块。组织病理学分析显示子宫内膜和卵巢均为II级同步子宫内膜样癌。该患者接受了三个周期的紫杉醇联合卡铂化疗。最后一个化疗周期七个月后,右侧肩部发现一个可触及的肿块,提示右肩胛骨有病变。骨扫描显示放射性摄取增加,凸显了疾病进展的不可预测性。诊断性成像方式的选择仍然具有挑战性。本病例强调了持续研究远处转移机制以及制定标准化诊断和治疗策略的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61fa/11222812/5ff3f8c9755a/gr1.jpg

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