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先天性和遗传性甲病。

[Translated article] Congenital and Hereditary Nail Disease.

机构信息

Departamento de Dermatología, Hospital Miguel Servet, Zaragoza, España.

Departamento de Dermatología, Hospital Miguel Servet, Zaragoza, España.

出版信息

Actas Dermosifiliogr. 2024 Sep;115(8):T773-T780. doi: 10.1016/j.ad.2024.07.011. Epub 2024 Jul 5.

Abstract

Nail disorders in newborns can show independently or as components of systemic illnesses or genodermatoses. The examination of these abnormalities is complex and sometimes challenging. However, familiarity with these disorders can significantly contribute to uncovering potential underlying conditions. This review includes the physiological nail changes seen within the first few months of life, such as Beau's lines, onychoschizia, koilonychia, congenital nail fold hypertrophy of the first digit, and onychocryptosis. This review also focuses on the most relevant congenital disorders reported and how to perform differential diagnosis. Finally, this review highlights those hereditary diseases in which nail involvement is crucial for diagnosis, such as nail-patella syndrome, congenital pachyonychia, or congenital dyskeratosis, among others.

摘要

新生儿的指甲疾病可以独立出现,也可以作为系统性疾病或遗传性皮肤病的组成部分。这些异常的检查很复杂,有时具有挑战性。然而,熟悉这些疾病可以大大有助于发现潜在的潜在疾病。本综述包括出生后头几个月出现的生理性指甲变化,如 Beau 线、甲纵裂、匙状甲、第一指先天性甲褶肥厚和甲下外生。本综述还重点介绍了报道的最相关的先天性疾病,以及如何进行鉴别诊断。最后,本综述强调了那些遗传性疾病,其中指甲受累对诊断至关重要,例如指甲髌骨综合征、先天性厚甲症或先天性角化不良症等。

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