Suppr超能文献

突破肠道范畴:免疫性血小板减少症作为溃疡性结肠炎一种罕见的肠外表现形式

Going Outside the Gut: Immune Thrombocytopenia Presenting as a Rare Extraintestinal Manifestation of Ulcerative Colitis.

作者信息

Rivera Ana P, Pellegrini James R, Saggar Tulika, Joy Melvin V, Sinha Atul, Gomez Sandra, Rizvon Kaleem

机构信息

Internal Medicine, Nassau University Medical Center, East Meadow, USA.

Gastroenterology and Hepatology, Nassau University Medical Center, East Meadow, USA.

出版信息

Cureus. 2024 Jun 7;16(6):e61888. doi: 10.7759/cureus.61888. eCollection 2024 Jun.

Abstract

A 26-year-old male with no significant medical history presented with hematochezia and was diagnosed with ulcerative colitis (UC) accompanied by immune thrombocytopenia (ITP) as an extraintestinal manifestation (EIM) of UC. This case report delves into the uncommon overlap between UC, a subtype of inflammatory bowel disease primarily affecting the colon and rectum, and ITP, an autoimmune condition leading to platelet destruction. The patient's atypical presentation and subsequent positive response to a treatment regimen targeting both UC and ITP underscores the necessity for a thorough and multifaceted diagnostic approach in individuals with UC, especially when faced with non-gastrointestinal symptoms like unexplained thrombocytopenia. The findings from this study enhance the understanding of UC's diverse manifestations and highlight its potential intersection with other autoimmune diseases, advocating for integrated care strategies in managing such intricate clinical cases.

摘要

一名26岁无重大病史的男性出现便血,被诊断为溃疡性结肠炎(UC),伴有免疫性血小板减少症(ITP),后者作为UC的肠外表现(EIM)。本病例报告深入探讨了主要影响结肠和直肠的炎症性肠病亚型UC与导致血小板破坏的自身免疫性疾病ITP之间罕见的重叠情况。患者的非典型表现以及随后针对UC和ITP的治疗方案产生的积极反应强调,对于UC患者,尤其是面对如不明原因血小板减少等非胃肠道症状时,采取全面且多方面的诊断方法很有必要。本研究结果增进了对UC多样表现的理解,并突出了其与其他自身免疫性疾病的潜在交叉点,倡导在管理此类复杂临床病例时采用综合护理策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a326/11227741/0539da80b52b/cureus-0016-00000061888-i01.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验