Lorenzo-Villalba Noel, Habib Charlene, Docquier Léa, Nasco Edward, Imperiale Alessio, Andrès Emmanuel, Terrade Jean Edouard
Service de Médecine Interne, Hôpitaux Universitaires de Strasbourg, Strasbourg, France.
Service de Médicine nucléaire, Hôpitaux Universitaires de Strasbourg, Strasbourg, France.
Eur J Case Rep Intern Med. 2024 Jul 1;11(7):004709. doi: 10.12890/2024_004709. eCollection 2024.
A 50-year-old patient with a history of limited cutaneous scleroderma began with polyarthralgia (left shoulder, elbows and hips) without stiffness or associated inflammatory syndrome. Treatment with oral anti-inflammatory drugs was started on suspicion of peripheral spondyloarthritis with partial response. This progressed with the appearance of stiffness and functional limitation of the hips as well as an increase in the inflammatory syndrome two weeks after onset. It was decided to perform an F-FDG-PET scan compatible with polymyalgia rheumatica. The patient was treated with oral corticosteroids with an excellent response after one week of treatment.
Polymyalgia rheumatica should be considered, even in young adults, with atypical clinical presentation.Post-infectious and paraneoplastic inflammatory rheumatism should be ruled out before considering the diagnosis of polymyalgia rheumatica.F-FDG-PET plays an important role in the positive diagnosis of PMR and in the differential diagnosis.
一名有局限性皮肤型硬皮病病史的50岁患者开始出现多关节痛(左肩、肘部和髋部),无僵硬或相关炎症综合征。因怀疑外周型脊柱关节炎开始使用口服抗炎药治疗,有部分反应。病情进展,出现髋部僵硬和功能受限,且发病两周后炎症综合征加重。决定进行与风湿性多肌痛相符的F-FDG-PET扫描。患者接受口服皮质类固醇治疗,治疗一周后反应良好。
即使在年轻人中,出现非典型临床表现时也应考虑风湿性多肌痛。在考虑诊断风湿性多肌痛之前,应排除感染后和副肿瘤性炎性风湿病。F-FDG-PET在风湿性多肌痛的阳性诊断和鉴别诊断中起重要作用。