Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY, USA.
Department of Informatics & Analytics, Dana Farber Cancer Institute, Boston, MA, USA.
Lancet Digit Health. 2024 Aug;6(8):e595-e600. doi: 10.1016/S2589-7500(24)00114-6. Epub 2024 Jul 9.
The rapid evolution of generative artificial intelligence (AI) models including OpenAI's ChatGPT signals a promising era for medical research. In this Viewpoint, we explore the integration and challenges of large language models (LLMs) in digital pathology, a rapidly evolving domain demanding intricate contextual understanding. The restricted domain-specific efficiency of LLMs necessitates the advent of tailored AI tools, as illustrated by advancements seen in the last few years including FrugalGPT and BioBERT. Our initiative in digital pathology emphasises the potential of domain-specific AI tools, where a curated literature database coupled with a user-interactive web application facilitates precise, referenced information retrieval. Motivated by the success of this initiative, we discuss how domain-specific approaches substantially minimise the risk of inaccurate responses, enhancing the reliability and accuracy of information extraction. We also highlight the broader implications of such tools, particularly in streamlining access to scientific research and democratising access to computational pathology techniques for scientists with little coding experience. This Viewpoint calls for an enhanced integration of domain-specific text-generation AI tools in academic settings to facilitate continuous learning and adaptation to the dynamically evolving landscape of medical research.
生成式人工智能(AI)模型的快速发展,包括 OpenAI 的 ChatGPT,标志着医学研究的一个充满希望的时代。在本观点中,我们探讨了大型语言模型(LLM)在数字病理学中的整合和挑战,数字病理学是一个快速发展的领域,需要复杂的上下文理解。由于 LLM 在特定领域的效率有限,因此需要出现定制的 AI 工具,近年来的一些进展,包括 FrugalGPT 和 BioBERT,就证明了这一点。我们在数字病理学方面的举措强调了特定领域 AI 工具的潜力,其中经过精心策划的文献数据库与用户交互的网络应用程序相结合,可以促进精确、有参考依据的信息检索。受这一举措的成功启发,我们讨论了特定领域方法如何大大降低不准确响应的风险,从而提高信息提取的可靠性和准确性。我们还强调了这些工具的更广泛影响,特别是在简化对科学研究的访问以及为编码经验较少的科学家普及计算病理学技术方面。本观点呼吁在学术环境中更加强大地整合特定领域的文本生成 AI 工具,以促进持续学习,并适应医学研究不断发展的动态格局。