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关注肾脏护理中的差距:将我们所知转化为我们所做。

Mind the gap in kidney care: translating what we know into what we do.

机构信息

University of Zurich, Epidemiology, Biostatistics and Prevention Institute, Department of Public and Global Health, Zurich, Switzerland.

Harvard Medical School, Brigham and Women's Hospital, Department of Medicine, Renal Division, Boston, Massachusetts, USA.

出版信息

J Bras Nefrol. 2024 Jul 5;46(3):e2024E007. doi: 10.1590/2175-8239-JBN-2024-E007en. eCollection 2024.

Abstract

Historically, it takes an average of 17 years for new treatments to move from clinical evidence to daily practice. Given the highly effective treatments now available to prevent or delay kidney disease onset and progression, this is far too long. Now is the time to narrow the gap between what we know and what we do. Clear guidelines exist for the prevention and management of common risk factors for kidney disease, such as hypertension and diabetes, but only a fraction of people with these conditions are diagnosed worldwide, and even fewer are treated to target. Similarly, the vast majority of people living with kidney disease are unaware of their condition, because it is often silent in the early stages. Even among patients who have been diagnosed, many do not receive appropriate treatment for kidney disease. Considering the serious consequences of kidney disease progression, kidney failure, or death, it is imperative that treatments are initiated early and appropriately. Opportunities to diagnose and treat kidney disease early must be maximized beginning at the primary care level. Many systematic barriers exist, ranging from the patient to the clinician to the health systems to societal factors. To preserve and improve kidney health for everyone everywhere, each of these barriers must be acknowledged so that sustainable solutions are developed and implemented without further delay.

摘要

从历史上看,新的治疗方法平均需要 17 年才能从临床证据转化为日常实践。鉴于现在有非常有效的治疗方法可以预防或延缓肾脏病的发生和进展,这个时间太长了。现在是缩小我们所知道的和我们所做的之间差距的时候了。预防和管理肾脏病常见风险因素(如高血压和糖尿病)的明确指南已经存在,但全世界只有一小部分有这些疾病的人被诊断出来,而接受针对性治疗的人就更少了。同样,绝大多数患有肾脏病的人都不知道自己的病情,因为在早期阶段它通常是无声的。即使在已经被诊断出的患者中,也有许多人没有得到适当的肾脏病治疗。考虑到肾脏病进展、肾衰竭或死亡的严重后果,必须尽早和适当地开始治疗。必须从初级保健层面最大限度地利用早期诊断和治疗肾脏病的机会。从患者到临床医生,再到医疗系统和社会因素,存在许多系统性障碍。为了保护和改善世界各地每个人的肾脏健康,必须承认这些障碍,以便制定和实施可持续的解决方案,不再拖延。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c672/11239182/aa237db81108/2175-8239-jbn-46-3-e2024E007-gf01.jpg

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