急性失代偿性心力衰竭患者的左心室和心房变形：一项初步研究。

Left Ventricular and Atrial Deformation in Patients with Acute Decompensated Heart Failure: A Pilot Study.

作者信息

Jurica Jakub, Péč Martin Jozef, Cingel Marek, Bolek Tomáš, Barbierik Vachalcová Marianna, Horná Simona, Galajda Peter, Mokáň Marián, Samoš Matej

机构信息

Department of Internal Medicine I, University Hospital Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Kollárova 2, 036 59 Martin, Slovakia.

Department of Cardiology, Teaching Hospital in Trenčín, 911 01 Trenčín, Slovakia.

出版信息

Diagnostics (Basel). 2024 Jun 27;14(13):1368. doi: 10.3390/diagnostics14131368.

DOI:10.3390/diagnostics14131368

PMID:39001258

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11240885/

Abstract

AIMS

The aims of this study were to compare global longitudinal strain of the left ventricle (LV-GLS) and reservoir strain of the left atrium (R-LAS) values between patients with acute decompensation of chronic heart failure (HF) and a control group.

METHODS

Sixteen patients admitted to our ward for acute decompensation of HF were enrolled in this study. Transthoracic echocardiography (TTE) with two-dimensional speckle-tracking analysis (2D ST) was performed in each patient. The patients were divided into two subgroups according to the value of left ventricular ejection fraction (EF) using a cut-off value of ≤40% to distinguish heart failure with reduced ejection fraction (HFrEF) from heart failure with preserved ejection fraction (HFpEF). The control group consisted of 16 individuals without a history of cardiovascular disease, each of whom underwent 2D ST analysis as well.

RESULTS

We found that LV-GLS and R-LAS were significantly lower in both the HFrEF and HFpEF subgroups in comparison with the control group (LV-GLS: -13.4 ± 4.7% vs. -19.7 ± 2.5%, ˂ 0.05; R-LAS: +12.2 ± 6.9% vs. +40.3 ± 7.4%, ˂ 0.05). Furthermore, there was a significant difference in LV-GLS (-9.6 ± 3.2% vs. -15.2 ± 4.3%, ˂ 0.05) but not in R-LAS (+13.7 ± 8.6% vs. +11.4 ± 6.2%) between the HFrEF and HFpEF subgroups.

CONCLUSIONS

Our study demonstrated a significant difference in LV-GLS and R-LAS in all enrolled HF patients compared to the control group. There was also a significant difference in LV-GLS between the HFrEF and HFpEF subgroups.

摘要

目的

本研究旨在比较慢性心力衰竭（HF）急性失代偿患者与对照组之间左心室整体纵向应变（LV-GLS）和左心房储存应变（R-LAS）值。

方法

本研究纳入了16名因HF急性失代偿入住我院病房的患者。对每位患者进行经胸超声心动图（TTE）检查，并采用二维斑点追踪分析（2D ST）。根据左心室射血分数（EF）值将患者分为两个亚组，以≤40%为临界值区分射血分数降低的心力衰竭（HFrEF）和射血分数保留的心力衰竭（HFpEF）。对照组由16名无心血管疾病史的个体组成，他们也均接受了2D ST分析。

结果

我们发现，与对照组相比，HFrEF和HFpEF亚组的LV-GLS和R-LAS均显著降低（LV-GLS：-13.4±4.7%对-19.7±2.5%，˂0.05；R-LAS：+12.2±6.9%对+40.3±7.4%，˂0.05）。此外，HFrEF和HFpEF亚组之间LV-GLS存在显著差异（-9.6±3.2%对-15.2±4.3%，˂0.05），但R-LAS无显著差异（+13.7±8.6%对+11.4±6.2%）。