Zhou You, Guiseppi Rodney, Banaee Touka
Department of Ophthalmology and Visual Sciences, University of Texas Medical Branch, Galveston, TX, USA.
Case Rep Ophthalmol. 2024 Jun 7;15(1):472-477. doi: 10.1159/000539190. eCollection 2024 Jan-Dec.
Posterior subtenon injection of triamcinolone acetonide (PSTA) is commonly done to treat refractory cases of macular edema. Complications may arise from the procedure as well as from the use of the periocular steroid medications. Side effects include subconjunctival hemorrhage, progression of cataract, scleral perforation (resulting in subretinal, subhyaloid, or intravitreal injection of the drug), retinal detachment, ptosis, orbital fat prolapse, orbital abscess, infectious scleritis, ocular hypertension, and scleral abscess. Here we describe a case of inadvertent subretinal triamcinolone acetonide (TA) deposition from a PSTA procedure without any adverse vision-threatening outcomes.
We report a patient who presented with a history of superior temporal left eye macula-off rhegmatogenous retinal detachment, which was successfully repaired with a scleral buckle (SB), pars plana vitrectomy, and gas placement. Due to persistent diplopia, the SB was removed after 1 year post-operatively. Due to the development of cystoid macular edema, a PSTA was performed after the patient failed topical steroids and NSAIDs. The procedure was halted early due to unexpected resistance during the injection. A dilated fundus exam showed the presence of subretinal triamcinolone acetonide. The patient was observed and found to have no complications with almost complete resolution of the triamcinolone acetonide after 3 months.
In previous SB patients, it is important to highlight the risk of globe penetration, subretinal deposition of TA, formation of retinal breaks, or reopening of prior retinal breaks with posterior subtenon injection, which could have adverse effects on the local retina as well as the risk of retinal detachment.
后Tenon囊下注射曲安奈德(PSTA)常用于治疗难治性黄斑水肿病例。该手术以及眼周类固醇药物的使用都可能引发并发症。副作用包括结膜下出血、白内障进展、巩膜穿孔(导致药物视网膜下、玻璃体下或玻璃体内注射)、视网膜脱离、上睑下垂、眶脂肪脱垂、眶脓肿、感染性巩膜炎、眼压升高和巩膜脓肿。在此,我们描述一例因PSTA手术意外导致曲安奈德(TA)视网膜下沉积但未出现任何威胁视力的不良后果的病例。
我们报告一名患者,其有左眼颞上方黄斑脱离的孔源性视网膜脱离病史,通过巩膜扣带术(SB)、玻璃体切割术和平坦部玻璃体切除术及气体填充成功修复。由于持续复视,术后1年取出了巩膜扣带。由于出现黄斑囊样水肿,在患者局部使用类固醇和非甾体抗炎药无效后进行了PSTA。由于注射过程中出现意外阻力,手术提前终止。散瞳眼底检查显示存在视网膜下曲安奈德。对患者进行观察,发现3个月后几乎完全吸收曲安奈德且无并发症。
对于既往接受过巩膜扣带术的患者,重要的是要强调后Tenon囊下注射存在眼球穿透、TA视网膜下沉积、视网膜裂孔形成或既往视网膜裂孔重新开放的风险,这可能对局部视网膜产生不利影响以及增加视网膜脱离的风险。