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肉毒毒素在复杂腹壁疝修补中的应用。

Application of botulinum toxin in the repair of a complex ventral hernia.

机构信息

Pediatric Surgery Department. Hospital Materno-Infantil Gregorio Marañón. Madrid (Spain).

出版信息

Cir Pediatr. 2024 Jul 9;37(3):133-136. doi: 10.54847/cp.2024.03.16.

Abstract

INTRODUCTION

Preoperative application of botulinum toxin type A has demonstrated to be safe and effective in the closure of complex ventral hernias in adults. However, its use in pediatrics has been little documented.

CASE REPORT

We present the case of a 22-month-old girl with a complex abdominal wall ventral hernia secondary to multiple neonatal laparotomies. In a first procedure, botulinum toxin was administered using an intramuscular approach at six sites of the muscle layers surrounding the defect, under general anesthesia and ultrasound control. 4 weeks later, an open hernia repair was conducted, without complications.

DISCUSSION

Botulinum toxin at low doses could facilitate the surgical treatment of complex ventral incisional hernias in children. Even though it is important to adjust dosage and anatomical reference points according to hernia type and patient age and weight, further studies are required to optimize these variables.

摘要

引言

在成人复杂腹壁疝的闭合中,术前应用肉毒毒素 A 已被证明是安全且有效的。然而,其在儿科中的应用却鲜有记录。

病例报告

我们报告了一例 22 个月大的女孩,因多次新生儿剖腹术导致复杂腹壁腹疝。在第一次手术中,在全身麻醉和超声控制下,在围绕缺损的肌肉层的六个部位,采用肌内注射的方式给予肉毒毒素。4 周后,进行了开放性疝修补术,无并发症。

讨论

低剂量肉毒毒素可有助于儿童复杂腹壁切口疝的手术治疗。尽管根据疝的类型以及患者的年龄和体重调整剂量和解剖参考点非常重要,但仍需要进一步的研究来优化这些变量。

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