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基于人工智能的磁共振成像在脑小血管病诊断中的应用。

Application of artificial intelligence-based magnetic resonance imaging in diagnosis of cerebral small vessel disease.

机构信息

Xuanwu Hospital, Capital Medical University, Beijing, China.

Department of Nuclear Medicine, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, China.

出版信息

CNS Neurosci Ther. 2024 Jul;30(7):e14841. doi: 10.1111/cns.14841.

Abstract

Cerebral small vessel disease (CSVD) is an important cause of stroke, cognitive impairment, and other diseases, and its early quantitative evaluation can significantly improve patient prognosis. Magnetic resonance imaging (MRI) is an important method to evaluate the occurrence, development, and severity of CSVD. However, the diagnostic process lacks quantitative evaluation criteria and is limited by experience, which may easily lead to missed diagnoses and misdiagnoses. With the development of artificial intelligence technology based on deep learning, the extraction of high-dimensional features in imaging can assist doctors in clinical decision-making, and it has been widely used in brain function and mental disorders, and cardiovascular and cerebrovascular diseases. This paper summarizes the global research results in recent years and briefly describes the application of deep learning in evaluating CSVD signs in MRI imaging, including recent small subcortical infarcts, lacunes of presumed vascular origin, vascular white matter hyperintensity, enlarged perivascular spaces, cerebral microbleeds, brain atrophy, cortical superficial siderosis, and cortical cerebral microinfarct.

摘要

脑小血管病(CSVD)是中风、认知障碍等疾病的重要病因,对其进行早期定量评估可以显著改善患者的预后。磁共振成像(MRI)是评估 CSVD 发生、发展和严重程度的重要方法。然而,其诊断过程缺乏定量评估标准且受经验限制,这可能容易导致漏诊和误诊。随着基于深度学习的人工智能技术的发展,对影像中高维特征的提取可以辅助医生进行临床决策,已广泛应用于脑功能和精神障碍、心血管和脑血管疾病。本文总结了近年来的全球研究结果,并简要描述了深度学习在 MRI 影像中评估 CSVD 征象中的应用,包括近期小的皮质下梗死、血管性腔隙、血管性脑白质高信号、扩大的血管周围间隙、脑微出血、脑萎缩、皮质表面铁沉积和皮质脑微梗死。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9968/11267174/02497e4909b4/CNS-30-e14841-g006.jpg

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