Department of Psychiatry, Medical University of Bialystok, pl. Wołodyjowskiego 2, 15-272 Białystok, Poland.
Nutrients. 2024 Jul 11;16(14):2228. doi: 10.3390/nu16142228.
Schizophrenia is a disease with a complex etiology that significantly impairs the functioning of patients. In recent years, there has been increasing focus on the importance of the gut microbiota in the context of the gut-brain axis. In our study, we analyzed data on the gut-brain axis in relation to schizophrenia, as well as the impacts of eating habits, the use of various supplements, and diets on schizophrenia. Additionally, the study investigated the impact of antipsychotics on the development of metabolic disorders, such as diabetes, dyslipidemia, and obesity. There may be significant clinical benefits to be gained from therapies supported by supplements such as omega-3 fatty acids, B vitamins, and probiotics. The results suggest the need for a holistic approach to the treatment of schizophrenia, incorporating both drug therapy and dietary interventions.
精神分裂症是一种病因复杂的疾病,会严重影响患者的功能。近年来,人们越来越关注肠道微生物群在肠道-大脑轴中的重要性。在我们的研究中,我们分析了与精神分裂症相关的肠道-大脑轴的数据,以及饮食习惯、各种补充剂和饮食对精神分裂症的影响。此外,该研究还调查了抗精神病药物对糖尿病、血脂异常和肥胖等代谢紊乱发展的影响。通过补充ω-3 脂肪酸、B 族维生素和益生菌等支持的治疗方法可能会带来显著的临床获益。研究结果表明,需要采用整体方法治疗精神分裂症,将药物治疗和饮食干预结合起来。