Pediatric Allergy Unit, Department of Life Sciences and Public Health, University Foundation Policlinico Gemelli IRCCS, Catholic University of the Sacred Heart, 00168 Rome, Italy.
Pediatric Unit, Department of Mother and Child Health, Salesi Children's Hospital, 60123 Ancona, Italy.
Nutrients. 2024 Jul 18;16(14):2317. doi: 10.3390/nu16142317.
Breastfeeding is the most important nutrition source for infants. However, managing breastfed infants with signs and symptoms related to food allergy can be difficult. Many studies have shown the presence of different food allergens in breast milk, but the clinical role of these antigens in human milk is still much debated. Milk is the main suspect in exclusively breastfed infants with signs and symptoms attributable to food allergy, even if other foods may be responsible. This narrative review analyzes the recommendations provided by international guidelines to determine the diagnosis and management of IgE-mediated and non-IgE-mediated food allergies in exclusively breastfed infants. Dietary restrictions in lactating mothers of infants with suspected FA are usually not necessary. Only in the very few cases where significant allergy signs and symptoms occur in the infant during exclusive breastfeeding should the lactating mother follow an elimination diet for the suspected food for a short period.
母乳喂养是婴儿最重要的营养来源。然而,对于有食物过敏相关症状和体征的母乳喂养婴儿的管理可能具有挑战性。许多研究表明母乳中存在不同的食物过敏原,但这些抗原在人乳中的临床作用仍存在很大争议。即使其他食物可能是罪魁祸首,但牛奶仍是有食物过敏相关症状和体征的纯母乳喂养婴儿的主要怀疑对象。本综述分析了国际指南中提供的建议,以确定纯母乳喂养婴儿 IgE 介导和非 IgE 介导食物过敏的诊断和管理。怀疑婴儿有 FA 的哺乳期母亲通常不需要限制饮食。只有在极少数情况下,婴儿在纯母乳喂养期间出现严重过敏症状和体征时,哺乳期母亲才应该在短时间内遵循可疑食物的排除饮食。