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食物蛋白质作为慢性病管理中的功能性成分:简要综述。

Food Proteins as Functional Ingredients in the Management of Chronic Diseases: A Concise Review.

机构信息

Department of Food and Nutritional Sciences, Tuskegee University, 1200 W. Montgomery Rd, Tuskegee, AL 36088, USA.

Biology Department, The Polytechnic, Ibadan 200132, Nigeria.

出版信息

Nutrients. 2024 Jul 19;16(14):2323. doi: 10.3390/nu16142323.

Abstract

Chronic diseases have emerged as a formidable global health concern, with their prevalence steadily rising over the years. Several approaches to addressing these concerns include the use of medications, which are often expensive, contain synthetic chemical substances, and have reported adverse effects. The use of foods, especially proteins, as an alternative approach to addressing chronic health concerns by treating and managing chronic diseases is increasing. This review evaluates the intriguing role of food proteins in mitigating chronic diseases and improving our understanding of the therapeutic potential of different protein types, including those derived from legumes, nuts, and seeds, dairy, fish, and numerous other sources. They have been reported to offer promising avenues for managing chronic diseases, including cardiovascular diseases, diabetes, chronic inflammation, weight management, bone health, glycemic control, muscle preservation, and many other health benefits. Although the exact mechanisms for these actions are still not properly elucidated, it is, however, understood that food proteins exert these health-beneficial effects by their unique nutritional and bioactive profiles, especially their bioactive peptides and amino acids. Practical applications are also discussed, including dietary interventions that are tailored towards incorporating protein-rich foods and the development of functional foods for disease prevention and management. Food proteins are a promising approach to combating chronic diseases that can turn around public health practices.

摘要

慢性疾病已成为一个严峻的全球健康问题,其发病率多年来稳步上升。解决这些问题的方法包括使用药物,这些药物通常很昂贵,含有合成化学物质,并且有不良反应的报道。人们越来越多地使用食物,特别是蛋白质,作为一种替代方法来治疗和管理慢性疾病,以解决慢性健康问题。本综述评估了食物蛋白质在减轻慢性疾病方面的有趣作用,并增进了我们对不同蛋白质类型(包括豆类、坚果和种子、乳制品、鱼类和许多其他来源的蛋白质)的治疗潜力的理解。据报道,它们为管理慢性疾病提供了有希望的途径,包括心血管疾病、糖尿病、慢性炎症、体重管理、骨骼健康、血糖控制、肌肉保护和许多其他健康益处。尽管这些作用的确切机制尚未得到充分阐明,但人们已经了解到,食物蛋白质通过其独特的营养和生物活性特性,特别是其生物活性肽和氨基酸,发挥这些有益健康的作用。还讨论了实际应用,包括针对摄入富含蛋白质的食物的饮食干预以及开发用于预防和管理疾病的功能性食品。食物蛋白质是一种有前途的治疗慢性疾病的方法,可以改变公共卫生实践。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/02c3/11279393/4345c0c867c7/nutrients-16-02323-g001.jpg

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