Goertz Lukas, Radomi Alexandra, Forbrig Robert, Pflaeging Muriel, Kabbasch Christoph, Liebig Thomas
Faculty of Medicine and University Hospital, Department of Radiology and Neuroradiology, University of Cologne, Cologne, Germany.
Institute of Neuroradiology, University Hospital Munich (LMU), Munich, Germany.
Interv Neuroradiol. 2024 Aug 1:15910199241264871. doi: 10.1177/15910199241264871.
The Contour Neurovascular System (CNS) is a novel intrasaccular flow disrupting device with a semi-3D cup-like shape for the treatment of intracranial aneurysms. This study investigates the potential and limitations of the CNS for embolization of aneurysm remnants after previous treatment.
Ten cases of aneurysm recurrence treatment with the CNS were analyzed from a single-center database. Technical success, procedural aspects, complications, and angiographic results were evaluated.
The aneurysms (median width: 5.3 mm, median neck width: 3.8 mm) were located in the anterior communicating artery (4), basilar tip (3), internal carotid artery (1), middle cerebral artery (1), and superior cerebellar artery (1). The aneurysms were initially treated endovascularly (9) and by clipping (1). Retreatment failed in one case where the smallest available CNS proved to be too small and had to be removed. Adjunctive coiling was performed in two large remnants of partially thrombosed basilar tip aneurysms. There were no procedural complications or morbidity. At a median follow-up of nine months, 4/8 (50%) aneurysms were completely occluded, 2/8 (25%) had neck remnants, and 2/8 (25%) had aneurysm remnants. The two aneurysm remnants were retreated with coiling and stent-assisted coiling, respectively.
CNS treatment of aneurysm remnants may be feasible, especially for shallow, wide-necked aneurysm geometries. Further studies are needed to identify aneurysm subsets that benefit from CNS retreatment and to define mid- and long-term occlusion rates.
轮廓神经血管系统(CNS)是一种新型的囊内血流阻断装置,呈半三维杯状,用于治疗颅内动脉瘤。本研究探讨了CNS用于栓塞既往治疗后动脉瘤残余的潜力和局限性。
从单中心数据库中分析了10例使用CNS进行动脉瘤复发治疗的病例。评估了技术成功率、手术过程、并发症和血管造影结果。
动脉瘤(中位宽度:5.3 mm,中位颈部宽度:3.8 mm)位于前交通动脉(4例)、基底动脉尖(3例)、颈内动脉(1例)、大脑中动脉(1例)和小脑上动脉(1例)。动脉瘤最初采用血管内治疗(9例)和夹闭治疗(1例)。1例再治疗失败,原因是最小的可用CNS被证明太小,不得不移除。对2例部分血栓形成的基底动脉尖动脉瘤的大残余进行了辅助弹簧圈栓塞。无手术并发症或致残情况。中位随访9个月时,8例动脉瘤中有4例(50%)完全闭塞,2例(25%)有颈部残余,2例(25%)有动脉瘤残余。对2例动脉瘤残余分别采用弹簧圈栓塞和支架辅助弹簧圈栓塞进行再治疗。
CNS治疗动脉瘤残余可能是可行的,尤其是对于浅的、宽颈的动脉瘤形态。需要进一步研究以确定从CNS再治疗中获益的动脉瘤亚组,并确定中长期闭塞率。