Qu Hongxue, Bian Lei
Department of Orthopedics and Traumatology, Yantai Hospital of Traditional Chinese Medicine Yantai 264001, Shandong, China.
Department of Imaging, Yantai Hospital of Traditional Chinese Medicine Yantai 264000, Shandong, China.
Am J Transl Res. 2024 Jul 15;16(7):2745-2755. doi: 10.62347/NUBB1946. eCollection 2024.
To compare the diagnostic accuracy of computed tomography (CT) scans and magnetic resonance imaging (MRI) in detecting occult hip fractures.
We conducted a systematic literature review and identified 12 articles involving 1,819 participants for inclusion. Data extraction and quality assessment were performed using the Quality Assessment of Diagnostic Accuracy Studies-2 tool. Publication bias was assessed with the Deek funnel plot asymmetry test. We conducted a meta-analysis using a random-effects model to derive pooled estimates of sensitivity, specificity, positive and negative likelihood ratios, and the diagnostic odds ratio, along with their 95% confidence intervals. A summary receiver operating characteristic curve was generated to illustrate the overall diagnostic accuracy.
The methodological quality of the included studies was high, with minimal concerns about the applicability of the tests in clinical settings. Both CT and MRI showed good diagnostic efficacy for occult hip fractures. However, MRI consistently outperformed CT, exhibiting significantly higher sensitivity, specificity, and likelihood ratios, thereby providing superior accuracy in confirming or excluding occult fractures. Meta-regression analysis revealed that sequence parameters and sample size significantly influenced the differences in sensitivity and specificity between CT and MRI.
Both CT and MRI are effective modalities for detecting occult hip fractures, with MRI demonstrating greater diagnostic accuracy. This meta-analysis supports the use of MRI when higher sensitivity and specificity are required in clinical practice.
比较计算机断层扫描(CT)和磁共振成像(MRI)在检测隐匿性髋部骨折方面的诊断准确性。
我们进行了一项系统的文献综述,确定了12篇涉及1819名参与者的文章纳入研究。使用诊断准确性研究质量评估-2工具进行数据提取和质量评估。采用Deek漏斗图不对称性检验评估发表偏倚。我们使用随机效应模型进行荟萃分析,以得出敏感性、特异性、阳性和阴性似然比以及诊断比值比的合并估计值及其95%置信区间。生成汇总受试者工作特征曲线以说明总体诊断准确性。
纳入研究的方法学质量较高,对这些检测方法在临床环境中的适用性几乎没有担忧。CT和MRI对隐匿性髋部骨折均显示出良好的诊断效能。然而,MRI始终优于CT,表现出显著更高的敏感性、特异性和似然比,从而在确认或排除隐匿性骨折方面具有更高的准确性。荟萃回归分析显示,序列参数和样本量显著影响CT和MRI之间敏感性和特异性的差异。
CT和MRI都是检测隐匿性髋部骨折的有效方法,MRI具有更高的诊断准确性。这项荟萃分析支持在临床实践中需要更高的敏感性和特异性时使用MRI。