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[家族性双白蛋白血症]

[Familial bisalbuminemia].

作者信息

Weigand Kilian, Weigand Kurt

机构信息

Klinik für Gastroenterologie, Gastrointestinale Tumortherapie und Diabetologie, Koblenz, Deutschland.

Stauferklinikum Schwäbisch Gmünd, Mutlangen, Deutschland.

出版信息

Inn Med (Heidelb). 2024 Oct;65(10):1036-1039. doi: 10.1007/s00108-024-01760-w. Epub 2024 Aug 9.

Abstract

Bisalbuminemia is characterized by two albumin peaks in the electrophoresis of serum. There are different forms of bisalbuminemia: inherited and acquired. The acquired form is mainly transitory, whereas the familial form is permanent. The frequency of bisalbuminemia in the general population has been reported to be between 0.0003 and 0.01%. This paper presents a case of familial bisalbuminemia as well as the family tree-to the extent obtainable. A married couple, in which the husband had bisalbuminemia, had seven children and 18 grandchildren. Bisalbuminemia was also found in two children and in two grandchildren.

摘要

双白蛋白血症的特征是血清电泳中有两个白蛋白峰。双白蛋白血症有不同形式:遗传性和获得性。获得性形式主要是暂时的,而家族性形式是永久性的。据报道,普通人群中双白蛋白血症的发生率在0.0003%至0.01%之间。本文介绍了一例家族性双白蛋白血症病例以及可获取范围内的家族谱系。一对夫妻,丈夫患有双白蛋白血症,他们育有7个子女和18个孙辈。在两个子女和两个孙辈中也发现了双白蛋白血症。

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