Aslan Hayrettin, Senocak Cagri, Haberal Hakan Bahadir, Guvenir Fahrettin Gorkem, Ibis Muhammed Arif, Sadioglu Fahri Erkan, Bozkurt Omer Faruk
Department of Urology, Ankara Ataturk Sanatoryum Training and Research Hospital, Ministry of Health, University of Health Sciences, Ankara, Turkey.
Department of Urology, Ankara Ataturk Sanatoryum Training and Research Hospital, Ministry of Health, University of Health Sciences, Ankara, Turkey.
J Pediatr Urol. 2024 Dec;20(6):1026-1033. doi: 10.1016/j.jpurol.2024.07.030. Epub 2024 Aug 5.
The prevelance of urinary system stone disease in children is emphasizing the need for minimally invasive treatments to decrease morbidity and recurrence risk. Percutaneous nephrolithotomy (PCNL) has emerged as a preferred approach for pediatric patients with complex stones due to its minimally invasive nature, including miniaturized and vacuum-assisted access sheaths, advanced laser technology and tubeless and outpatient procedures. However, adult scoring systems have proven ineffective in predicting success and complications in pediatric PCNL. This highlights the need for specialized scoring systems, such as the Stone-Kidney Size (SKS) scoring system, tailored to pediatric patients and will be evaluated in our study for its association with the stone-free rate (SFR) and complications.
The data of 144 patients aged <17 years who had undergone PCNL between January 2008 and December 2019 were evaluated retrospectively. Demographics, stone characteristics, perioperative/postoperative outcomes were recorded for each patient. The SKS scoring system comprises the stone kidney index (SKI) and the number of stones, assigns one or two points based on single or multiple stones and an SKI value of <0.3 or ≥0.3, respectively. The SKI is computed by dividing the stone's longest axis by the kidney's longest axis. Residual stones less than 4 mm on non-contrast computed tomography are considered clinically insignificant residual fragments (CIRFs). Stone-free and CIRF patients were considered successful results. The relationship between the SKS scoring system and SFR, success, and complication rates after surgery was investigated. Statistical analyses were conducted using SPSS 22.0 software.
The SFR was 67.36% and 74.31% when CIRF patients were included, respectively, with a complication rate of 27%. In multivariate analysis, stone treatment history, stone burden, and SKS score were statistically significantly associated with SFR (p < 0.001, p = 0.032, p < 0.001, respectively). Furthermore, the SKS score was the only variable that showed a statistically significant relationship with success. No significant association was found between SKS score and complications (p = 0.342).
Our study demonstrates a relationship between the SKS scoring system and SFR in pediatric PCNL patients. However, shortcomings have been observed in its capacity to accurately predict post-PCNL complications. Despite being a retrospective analysis and having a single-center design, our study externally validates the relationship between the SKS scoring system and SFR after pediatric PCNL.
The SKS scoring system is associated with SFR in pediatric patients undergoing PCNL; however, this relationship has not been established for complications.
儿童泌尿系统结石病的患病率凸显了采用微创治疗以降低发病率和复发风险的必要性。经皮肾镜取石术(PCNL)因其微创特性,包括小型化和真空辅助穿刺鞘、先进的激光技术以及无管化和门诊手术等,已成为治疗复杂结石儿科患者的首选方法。然而,事实证明成人评分系统在预测儿科PCNL的成功率和并发症方面效果不佳。这凸显了针对儿科患者的专门评分系统的必要性,例如结石 - 肾脏大小(SKS)评分系统,本研究将对其与结石清除率(SFR)和并发症的相关性进行评估。
回顾性评估2008年1月至2019年12月期间接受PCNL的144例年龄小于17岁患者的数据。记录每位患者的人口统计学资料、结石特征、围手术期/术后结果。SKS评分系统包括结石肾脏指数(SKI)和结石数量,根据结石为单个或多个以及SKI值<0.3或≥0.3分别赋予1分或2分。SKI通过将结石的最长轴除以肾脏的最长轴来计算。非增强计算机断层扫描显示残留结石小于4毫米被视为临床无意义的残留碎片(CIRF)。结石清除和CIRF患者被视为手术成功结果。研究SKS评分系统与SFR、手术成功率和并发症发生率之间的关系。使用SPSS 22.0软件进行统计分析。
纳入CIRF患者时,SFR分别为67.36%和74.31%,并发症发生率为27%。多因素分析显示,结石治疗史、结石负荷和SKS评分与SFR在统计学上显著相关(分别为p < 0.001、p = 0.032、p < 0.001)。此外,SKS评分是唯一与手术成功呈统计学显著关系的变量。未发现SKS评分与并发症之间存在显著关联(p = 0.342)。
我们的研究表明SKS评分系统与儿科PCNL患者的SFR之间存在关联。然而,其准确预测PCNL术后并发症方面存在不足。尽管本研究为回顾性分析且采用单中心设计,但外部验证了SKS评分系统与儿科PCNL术后SFR之间的关系。
SKS评分系统与接受PCNL的儿科患者的SFR相关;然而,尚未证实该关系与并发症有关。