Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Department of ENT, Head and Neck Surgery, Emergency University Hospital, 050098 Bucharest, Romania.
Medicina (Kaunas). 2024 Aug 18;60(8):1340. doi: 10.3390/medicina60081340.
Patients with advanced head and neck tumors require salvage surgery as a last resort. These extensive surgeries pose the challenge of complex reconstructions. The head and neck surgeon undertaking such complex cases needs to master different flaps. The team managing these patients needs input from various specialists, along with otorhinolaryngologists, plastic surgeons, maxillofacial surgeons, vascular surgeons, experienced radiologists, dedicated pathologists, oncologists and radiation therapists. We focus on the optimum solution between oncologic resections and the future quality of life of patients and overall survival. Each complex case requires a personalized medicine approach. This scoping review aims to assess the efficacy and outcomes of complex reconstructions using various flaps for head and neck tumors, with a focus on free flaps and emerging techniques. A systematic search of the literature was conducted following PRISMA guidelines, resulting in the inclusion of 44 articles that met the predefined criteria in the last 10 years. The included studies encompassed diverse patient populations and evaluated various surgical techniques, outcomes, complications, and advancements in head and neck reconstruction. The review identified a variety of flaps utilized in head and neck tumor reconstruction, including free flaps such as the radial forearm, anterolateral thigh, scapular tip, and myocutaneous flaps, among others. The success rates for free flap reconstructions ranged from 85% to 100%, with notable variations attributed to patient selection, tumor characteristics, and surgical expertise. Complications such as flap necrosis, infection, hematoma, and donor site morbidity were documented across studies, highlighting the importance of meticulous surgical planning and postoperative care. Furthermore, the review revealed emerging techniques such as computer-aided design, virtual surgery, stereolithographic models, customized implants, tissue engineering, and allotransplants, offering promising reconstructive armamentarium. Advances in surgical techniques and emerging technologies hold promise for further enhancing reconstructive outcomes, minimizing morbidity, and improving patient quality of life.
晚期头颈部肿瘤患者需要进行挽救性手术,这是最后的治疗手段。这些广泛的手术带来了复杂重建的挑战。进行此类复杂病例的头颈部外科医生需要掌握不同的皮瓣。管理这些患者的团队需要来自耳鼻喉科医生、整形外科医生、颌面外科医生、血管外科医生、有经验的放射科医生、专门的病理学家、肿瘤学家和放射治疗师等各种专家的意见。我们专注于在肿瘤切除和患者未来生活质量以及总生存率之间找到最佳解决方案。每个复杂病例都需要采用个性化的医疗方法。本综述旨在评估使用各种皮瓣对头颈部肿瘤进行复杂重建的疗效和结果,重点关注游离皮瓣和新兴技术。根据 PRISMA 指南进行了系统的文献搜索,纳入了过去 10 年中符合预设标准的 44 篇文章。纳入的研究涵盖了不同的患者人群,并评估了各种手术技术、结果、并发症以及头颈部重建的进展。综述确定了多种用于头颈部肿瘤重建的皮瓣,包括游离皮瓣,如桡侧前臂、前外侧股、肩胛骨尖端和肌皮瓣等。游离皮瓣重建的成功率为 85%至 100%,但由于患者选择、肿瘤特征和手术技能的不同,成功率有显著差异。研究报告了各种并发症,如皮瓣坏死、感染、血肿和供区并发症,这突出了精细手术计划和术后护理的重要性。此外,综述还揭示了一些新兴技术,如计算机辅助设计、虚拟手术、立体光刻模型、定制植入物、组织工程和同种异体移植,为重建提供了有前途的手段。手术技术和新兴技术的进步有望进一步提高重建效果、降低发病率并提高患者的生活质量。