State Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Institute of Microbiology, Guangdong Academy of Sciences, 100 Central Xianlie Road, Guangzhou, 510070, China; Liaoning Key Lab of Lignocellulose Chemistry and BioMaterials, Liaoning Collaborative Innovation Center for Lignocellulosic Biorefinery, College of Light Industry and Chemical Engineering, Dalian Polytechnic University, Dalian 116034, China; Guangdong Dimei New Materials Technology Co. Ltd., 100 Central Xianlie Road, Guangzhou, 510070, China.
State Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Institute of Microbiology, Guangdong Academy of Sciences, 100 Central Xianlie Road, Guangzhou, 510070, China; Liaoning Key Lab of Lignocellulose Chemistry and BioMaterials, Liaoning Collaborative Innovation Center for Lignocellulosic Biorefinery, College of Light Industry and Chemical Engineering, Dalian Polytechnic University, Dalian 116034, China.
Int J Biol Macromol. 2024 Nov;279(Pt 2):135169. doi: 10.1016/j.ijbiomac.2024.135169. Epub 2024 Aug 30.
Replacing fossil resource with biomass is one of the promising approaches to reduce our carbon footprint. Lignin is one of the three major components of lignocellulosic biomass, accounting for 10-35 wt% of dried weight of the biomass. Hydrogenolytic depolymerization of lignin is attracting increasing attention because of its capacity of utilizing lignin in its uncondensed form and compatibility with the biomass fractionation processes. Lignin is a natural aromatic polymer composed of a variety of monolignols associated with a series of lignin linkage motifs. Hydrogenolysis cleaves various ether bonds in lignin and releases phenolic monomers which can be further upgraded into valuable products, i.e., drugs, terephthalic acid, phenol. This review provides an overview of the state-of-the-art advances of the reagent (lignin), products (hydrol lignin), mass balance, and mechanism of the lignin hydrogenolysis reaction. The chemical structure of lignin is reviewed associated with the free radical coupling of monolignols and the chemical reactions of lignin upon isolation processes. The reactions of lignin linkages upon hydrogenolysis are discussed. The components of hydrol lignin and the selectivity production of phenolic monomers are reviewed. Future challenges on hydrogenolysis of lignin are proposed. This article provides an overview of lignin hydrogenolysis reaction which shows light on the generation of optimized lignin ready for hydrogenolytic depolymerization.
用生物质替代化石资源是减少碳排放的有前途的方法之一。木质素是木质纤维素生物质的三大组成部分之一，占生物质干重的 10-35wt%。由于其能够利用未缩合的木质素形式以及与生物质分级过程的兼容性，木质素的氢解解聚受到越来越多的关注。木质素是一种天然芳香族聚合物，由各种与一系列木质素连接基序相关的单体木质醇组成。氢解可裂解木质素中的各种醚键，并释放出酚类单体，可进一步升级为有价值的产品，如药物、对苯二甲酸、苯酚。本文综述了木质素氢解反应的试剂（木质素）、产物（水解木质素）、质量平衡和机理的最新进展。综述了木质素的化学结构，包括单体木质醇的自由基偶联以及木质素在分离过程中的化学反应。讨论了木质素键在氢解过程中的反应。综述了水解木质素的组成和酚类单体的选择性生成。提出了木质素氢解的未来挑战。本文综述了木质素氢解反应，为生成优化的木质素以进行氢解解聚提供了启示。
