Rev Sci Tech. 2024 Aug;43:168-176. doi: 10.20506/rst.43.3529.
Misuse and overuse of antimicrobials in livestock production are identified as drivers for antimicrobial resistance (AMR). To improve decision-making concerning livestock health, it is important to understand the impact of AMR in livestock and aquaculture, within and beyond farm level, as well as expenditure on antimicrobial use (AMU). Such understanding provides grounds for systematic disease prioritisation and establishes a baseline for understanding the value of different strategies to mitigate animal health problems and for the monitoring and evaluation of the impact of those strategies. Yet limited data availability and quality surrounding AMU and AMR create barriers to furthering the knowledge of such impact. These data constraints are also more prevalent in contexts that lack the necessary resources to develop and maintain systematic and centralised data collection and collation systems. Even in regions with robust AMU and AMR monitoring systems in place, data limitations remain, such that the expenditure on antimicrobials and impacts of AMR remain unclear. Additionally, the current research funding strategies have been less focused on primary data collection, adding further barriers to filling the data void and reducing the global AMU/AMR knowledge gap. To work around the data scarcity and leverage previous and ongoing research efforts, it is vital to gain comprehensive knowledge of the people, projects and research consortia dedicated to the topic of AMU/AMR.
在畜牧业生产中,抗生素的误用和滥用被认为是导致抗生素耐药性(AMR)的驱动因素。为了改善与畜牧业健康相关的决策,了解 AMR 在农场内外的畜牧业和水产养殖中的影响,以及抗生素使用(AMU)的支出情况非常重要。这种理解为系统地确定疾病优先级提供了依据,并为了解不同策略减轻动物健康问题的价值以及监测和评估这些策略的影响奠定了基础。然而,围绕 AMU 和 AMR 的有限数据可用性和质量给进一步了解这种影响带来了障碍。这些数据限制在缺乏必要资源来开发和维护系统和集中的数据收集和整理系统的情况下更为普遍。即使在已经建立了强大的 AMU 和 AMR 监测系统的地区,数据限制仍然存在,因此对抗生素的支出和 AMR 的影响仍不清楚。此外,目前的研究资金策略较少关注原始数据的收集,这进一步加剧了填补数据空白和缩小全球 AMU/AMR 知识差距的障碍。为了克服数据短缺问题并利用以前和正在进行的研究工作,全面了解致力于 AMU/AMR 主题的人员、项目和研究联盟至关重要。