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颈椎前凸增加与C5麻痹患者恢复率降低相关。

Increased Change in Cervical Lordosis Is Associated With Decreased Rate of Recovery in Patients With C5 Palsy.

作者信息

Frazzetta Joseph N, Pecoraro Nathan, Jusue-Torres Ignacio, Arnold Paul M, Hofler Ryan, Jones G Alexander, Nockels Russ

机构信息

Department of Neurological Surgery, School of Medicine, Loyola University Stritch, Maywood, IL.

Department of Neurological Surgery, Mayo Clinic, Rochester, MN.

出版信息

Clin Spine Surg. 2025 Apr 1;38(3):E152-E159. doi: 10.1097/BSD.0000000000001680. Epub 2024 Sep 3.

Abstract

STUDY DESIGN

A retrospective chart review.

OBJECTIVE

The authors aim to investigate the role of clinical and radiographic parameters in patients who underwent posterior cervical surgery, and their association with C5 palsy severity and time to recovery.

BACKGROUND

Postoperative C5 palsy affects 1%-30% of patients undergoing posterior decompression, with or without fusion. Causation and avoidance of this complication remain widely debated.

MATERIALS AND METHODS

A single institution review of patients who underwent posterior cervical spine surgery was focused on using specific Common Procedural Technology codes associated with the patient population of interest. Patients were excluded if they had inadequate pre and postoperative imaging, as well as a history of prior cervical spine surgery, concurrent anterior surgery, intradural pathology, spinal tumor, or spinal trauma. Radiographic measurements of the pre and postoperative images were completed with subsequent intraclass correlation coefficient analysis to confirm the precision of measurements.

RESULTS

Out of 105 total patients, 35 (33%) patients developed a C5 palsy. Twenty-four (69%) of those palsies completely resolved, with a median time to recovery of 8 months. Preoperative demographics and radiographic parameters demonstrated heterogeneity among those patients who did and did not have a resolution of palsy. Patients with increased change in C2-C7 lordosis ( P = 0.011) after surgery were associated with decreased likelihood of recovery. Patients without a smoking history ( P = 0.009) had an increased likelihood of recovering from C5 palsy.

CONCLUSIONS

The degree of increased lordosis in the treatment of degenerative cervical disease plays a role in the rate of recovery from C5 palsy. This should be considered during preoperative planning in determining the amount of lordosis desired. In addition, patients without a smoking history were associated with a higher rate of recovery.

LEVEL OF EVIDENCE

Level IV.

摘要

研究设计

一项回顾性图表审查。

目的

作者旨在研究临床和影像学参数在接受颈椎后路手术患者中的作用,以及它们与C5麻痹严重程度和恢复时间的关联。

背景

术后C5麻痹影响1% - 30%接受后路减压手术(无论是否融合)的患者。这种并发症的病因及预防仍存在广泛争议。

材料与方法

对一家机构中接受颈椎后路手术的患者进行回顾,重点使用与感兴趣患者群体相关的特定通用程序技术代码。如果患者术前和术后影像学资料不完整,以及有颈椎前路手术史、同期前路手术、硬脊膜内病变、脊柱肿瘤或脊柱创伤史,则被排除。对术前和术后图像进行影像学测量,并随后进行组内相关系数分析以确认测量的精度。

结果

在总共105例患者中,35例(33%)出现C5麻痹。其中24例(69%)麻痹完全恢复,恢复的中位时间为8个月。术前人口统计学和影像学参数显示,麻痹是否恢复的患者之间存在异质性。术后C2 - C7前凸变化增加(P = 0.011)的患者恢复可能性降低。无吸烟史的患者(P = 0.009)从C5麻痹中恢复的可能性增加。

结论

退行性颈椎疾病治疗中前凸增加的程度在C5麻痹的恢复率中起作用。在术前规划确定所需前凸量时应考虑这一点。此外,无吸烟史的患者恢复率较高。

证据水平

四级。

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