Inauen Joseph, Barry Simone
Department of Thoracic Medicine Royal Adelaide Hospital Adelaide South Australia Australia.
Respirol Case Rep. 2024 Sep 10;12(9):e70004. doi: 10.1002/rcr2.70004. eCollection 2024 Sep.
This clinical case highlights the diagnostic challenges encountered in a young adult smoker presenting with undifferentiated pulmonary nodules. Initial investigations were inconclusive, necessitating surgical lung biopsy due to the nodules' size and location. The histopathological examination revealed pulmonary Langerhans cell histiocytosis (PLCH). This emphasizes the importance of considering PLCH in the differential diagnosis of pulmonary nodules, particularly in smokers. Moreover, it underscores the value of surgical biopsy in cases where other diagnostic techniques are limited. Early recognition and accurate diagnosis are crucial for optimal management and outcomes in PLCH.
本临床病例突出了一名年轻成年吸烟者出现未分化肺结节时所面临的诊断挑战。初步检查结果不明确,由于结节的大小和位置,需要进行手术肺活检。组织病理学检查显示为肺朗格汉斯细胞组织细胞增多症(PLCH)。这强调了在肺结节的鉴别诊断中考虑PLCH的重要性,尤其是在吸烟者中。此外,它还凸显了在其他诊断技术有限的情况下手术活检的价值。早期识别和准确诊断对于PLCH的最佳管理和预后至关重要。