From the Department of Neurology (S.H.), Duke University School of Medicine, Durham, NC; Department of Neurology (B.O.), University California San Francisco; Department of Medicine Statistics Core (D.M.), University California Los Angeles; and Department of Neurology (A.T.), University Southern California, Los Angeles.
Neurology. 2024 Oct 8;103(7):e209807. doi: 10.1212/WNL.0000000000209807. Epub 2024 Sep 11.
The new American Heart Association Life's Essential 8 construct of ideal cardiovascular health now includes sleep duration. Little is known, however, about sleep duration in individuals with prior stroke. Our objective was to compare sleep duration among individuals with and without prior stroke.
Using the National Health and Nutrition Examination Surveys (NHANES) database (2005-2018), individuals 18 years or older were identified (n = 37,987 without self-reported stroke; n = 1,572 with self-reported stroke). Prevalence of normal sleep duration (7-8 or 6-8 hours/night because of multiple definitions in the literature) was compared between persons with and without self-reported history of stroke using the Rao-Scott χ test. Multinomial logistic regression analysis was used to evaluate the relationship between prior stroke and abnormal sleep before and after adjusting for demographic and clinical variables.
Compared with individuals without stroke, those with prior stroke were more likely to report >8 hours/night (unadjusted odds ratio (OR) 2.03, 95% confidence interval (CI) 1.64-2.51), <7 hours/night (1.29, 1.08-1.53), and <6 hours/night (1.87, 1.53-2.29). After adjustment, these associations were attenuated (adjusted OR 1.54, 95% CI 1.22-1.94 and 1.15, 0.96-1.38 and 1.50, 1.21-1.85).
US stroke survivors are more likely to have abnormal sleep duration than those without prior stroke. Limitations of this study include the cross-sectional and self-reported nature of the data.
新的美国心脏协会生命基本 8 项理想心血管健康指标现在包括睡眠时间。然而,对于有既往卒中史的个体的睡眠持续时间知之甚少。我们的目的是比较有和无既往卒中史个体的睡眠持续时间。
利用国家健康和营养调查(NHANES)数据库(2005-2018 年),确定 18 岁或以上的个体(无自我报告卒中史的个体 37987 例;有自我报告卒中史的个体 1572 例)。使用 Rao-Scott χ 检验比较有和无自我报告卒中史个体的正常睡眠时间(7-8 或 6-8 小时/夜,因为文献中有多种定义)的发生率。使用多项逻辑回归分析评估既往卒中与调整人口统计学和临床变量前后异常睡眠之间的关系。
与无卒中个体相比,有既往卒中个体更有可能报告 >8 小时/夜(未调整的优势比(OR)2.03,95%置信区间(CI)1.64-2.51)、<7 小时/夜(1.29,1.08-1.53)和<6 小时/夜(1.87,1.53-2.29)。调整后,这些关联减弱(调整后的 OR 1.54,95%CI 1.22-1.94 和 1.15,0.96-1.38 和 1.50,1.21-1.85)。
美国卒中幸存者的异常睡眠时间比无既往卒中的个体更常见。本研究的局限性包括数据的横断面和自我报告性质。