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在印度东部一家三级护理医院使用FullPIERS(先兆子痫综合风险评估)模型预测先兆子痫孕产妇不良结局

Prediction of Adverse Maternal Outcomes in Preeclampsia Using the FullPIERS (Preeclampsia Integrated Estimate of Risk) Model in a Tertiary Care Hospital of Eastern India.

作者信息

Burman Dipon, Das Sanjukta, Burman Jayeeta, Sembiah Sembagamuthu

机构信息

Obstetrics and Gynaecology, Balurghat Super Specialty Hospital, Balurghat, IND.

Obstetrics and Gynaecology, Gangarampur Super Specialty Hospital, Gangarampur, IND.

出版信息

Cureus. 2024 Aug 12;16(8):e66664. doi: 10.7759/cureus.66664. eCollection 2024 Aug.

Abstract

INTRODUCTION

Preeclampsia, characterized by hypertensive disorders and systemic inflammatory response, remains a leading cause of maternal morbidity and mortality globally. Effective risk assessment tools are crucial for predicting adverse maternal outcomes.

OBJECTIVE

This study evaluates the performance of the fullPIERS (Preeclampsia Integrated Estimate of Risk) model in predicting adverse maternal outcomes within 24 hours of admission for preeclampsia.

METHODS

A cross-sectional study was conducted over one year, involving 100 preeclamptic patients admitted to Nil Ratan Sircar Medical College & Hospital (NRSMCH). Predictor variables were collected within 24 hours of admission and analyzed using the fullPIERS model.

RESULTS

The fullPIERS model effectively stratified maternal risk. Adverse outcomes were significantly associated with systolic blood pressure (BP) ≥ 140 mmHg, diastolic BP ≥ 90 mmHg, oxygen saturation ≤ 95%, frontal headache, visual disturbances, chest pain/dyspnea, and abnormal random blood sugar, albumin, alanine aminotransferase, platelet count, and creatinine levels. A fullPIERS score ≥ 30 was strongly predictive of adverse maternal outcomes.

CONCLUSION

The fullPIERS model is a valuable tool for predicting adverse maternal outcomes in preeclampsia, aiding in timely and effective clinical decision-making.

摘要

引言

子痫前期以高血压疾病和全身炎症反应为特征,仍然是全球孕产妇发病和死亡的主要原因。有效的风险评估工具对于预测孕产妇不良结局至关重要。

目的

本研究评估全PIERS(子痫前期综合风险评估)模型在预测子痫前期患者入院24小时内孕产妇不良结局方面的性能。

方法

进行了一项为期一年的横断面研究,纳入了100例入住尼尔·拉坦·西卡尔医学院及医院(NRSMCH)的子痫前期患者。在入院24小时内收集预测变量,并使用全PIERS模型进行分析。

结果

全PIERS模型有效地对孕产妇风险进行了分层。不良结局与收缩压(BP)≥140 mmHg、舒张压≥90 mmHg、血氧饱和度≤95%、前额头痛、视觉障碍、胸痛/呼吸困难以及随机血糖、白蛋白、丙氨酸转氨酶、血小板计数和肌酐水平异常显著相关。全PIERS评分≥30强烈预测孕产妇不良结局。

结论

全PIERS模型是预测子痫前期孕产妇不良结局并有助于及时有效临床决策的有价值工具。

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本文引用的文献

1
Preeclampsia at term: evidence of disease heterogeneity based on the profile of circulating cytokines and angiogenic factors.
Am J Obstet Gynecol. 2024 Apr;230(4):450.e1-450.e18. doi: 10.1016/j.ajog.2023.10.002. Epub 2023 Oct 6.
2
Combining Biomarkers to Predict Pregnancy Complications and Redefine Preeclampsia: The Angiogenic-Placental Syndrome.
Hypertension. 2020 Apr;75(4):918-926. doi: 10.1161/HYPERTENSIONAHA.119.13763. Epub 2020 Feb 17.
4
Hypertension in pregnancy: Pathophysiology and treatment.
SAGE Open Med. 2019 Apr 10;7:2050312119843700. doi: 10.1177/2050312119843700. eCollection 2019.
5
[Potential value of placental angiogenic factors as biomarkers in preeclampsia for clinical physicians].
Nephrol Ther. 2019 Nov;15(6):413-429. doi: 10.1016/j.nephro.2018.10.005. Epub 2019 Mar 30.
6
Pre-eclampsia: pathogenesis, novel diagnostics and therapies.
Nat Rev Nephrol. 2019 May;15(5):275-289. doi: 10.1038/s41581-019-0119-6.
7
Assessment of the fullPIERS Risk Prediction Model in Women With Early-Onset Preeclampsia.
Hypertension. 2018 Apr;71(4):659-665. doi: 10.1161/HYPERTENSIONAHA.117.10318. Epub 2018 Feb 12.
9
Prediction of Adverse Maternal Outcomes in Preeclampsia Using a Risk Prediction Model.
J Obstet Gynaecol India. 2016 Oct;66(Suppl 1):104-11. doi: 10.1007/s13224-015-0779-5. Epub 2015 Nov 11.
10
Hypertensive disorders in pregnancy among pregnant women in a Nigerian Teaching Hospital.
Niger Med J. 2014 Sep;55(5):384-8. doi: 10.4103/0300-1652.140377.

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