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高血压合并左心室肥厚的诊断与治疗进展。

Progress in diagnosis and treatment of hypertension combined with left ventricular hypertrophy.

机构信息

Department of Cardiology, First Hospital of China Medical University, Shenyang, Liaoning Province, China.

Department of Cardiology, Yixian People's Hospital, Jinzhou, Liaoning Province, China.

出版信息

Ann Med. 2024 Dec;56(1):2405080. doi: 10.1080/07853890.2024.2405080. Epub 2024 Sep 20.

Abstract

BACKGROUND

Hypertension, a worldwide cardiovascular issue, is known to result in significant damage to the left ventricle. Left ventricular hypertrophy refers to an increase in ventricular mass, which is not only the primary independent risk factor for cardiovascular disease onset but also independently related to the risk of death.

OBJECTIVES

We sought to synthesize the existing literature on the occurrence and correlation between hypertension and left ventricular hypertrophy and the progress.

METHODS

A scoping review was performed based on the methodological framework developed by Arksey & O'Malley. Search in the Pubmed database with no language restrictions, as of September 1, 2024.

RESULTS

Of the 8110 articles retrieved, 110 were finally included. The selected articles were published between 1987 and 2024, with 55.5% (61/110) of the studies in the last five years and 14.5% (16/110) of 2024. The studies covered diagnosis, epidemiology, pathophysiology, prognosis, and treatment of hypertension with left ventricular hypertrophy.

CONCLUSION

The literature reviewed suggests that studies on hypertension combined with left ventricular hypertrophy covered a variety of clinical progress, especially the clinical trial results of some new drugs that may bring great hope for treatment.

摘要

背景

高血压是一种全球性的心血管问题,已知会对左心室造成严重损害。左心室肥厚是指心室质量的增加,它不仅是心血管疾病发病的主要独立危险因素,而且还与死亡风险独立相关。

目的

我们旨在综合现有关于高血压与左心室肥厚的发生和相关性以及进展的文献。

方法

根据 Arksey 和 O'Malley 制定的方法框架进行范围综述。截至 2024 年 9 月 1 日,在 Pubmed 数据库中进行无语言限制的搜索。

结果

在检索到的 8110 篇文章中,最终有 110 篇被纳入。所选文章的发表时间在 1987 年至 2024 年之间,其中 55.5%(61/110)的研究在过去五年内进行,14.5%(16/110)的研究在 2024 年进行。这些研究涵盖了高血压合并左心室肥厚的诊断、流行病学、病理生理学、预后和治疗。

结论

综述文献表明,关于高血压合并左心室肥厚的研究涵盖了多种临床进展,特别是一些新药的临床试验结果可能为治疗带来很大希望。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad79/11418038/1daf7f4923d5/IANN_A_2405080_F0001_C.jpg

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