Ortmann Laura, Wehrmann Melissa, Flores Ricky, Kerns Ellen
Department of Pediatrics, University of Nebraska Medical Center, Omaha, NE, USA.
Division of Care Transformation, Children's Nebraska, 8200 Dodge St., Omaha, NE, 68114, USA.
Pediatr Cardiol. 2024 Sep 20. doi: 10.1007/s00246-024-03658-8.
Newborns with coarctation of the aorta are a potentially vulnerable population whose diagnosis could have been impacted by the COVID-19 pandemic. The objectives of this study were to assess if there was delayed diagnosis of infants with coarctation and if they had higher acuity prior to repair after the start of the pandemic. The Pediatric Health Information Systems database was queried for patients less than three months of age who underwent surgical repair or palliation of coarctation of the aorta. Patients were divided into three time periods: (1) pre-COVID (October 2017-December 2019), (2) early COVID (January 2020-December 2020), and (3) late COVID (January 2021-December 2021). The outcomes were age at repair and pre-procedure acuity. Among the 4885 patients, the median time to repair was 10 days during all time periods. Use of pre-procedure mechanical ventilation, vasopressors, and extracorporeal membranous oxygenation did not increase after the start of the pandemic. Median length of hospital stay increased after the start of the pandemic and did not return to baseline (22 days, 24 days, and 25 days, sequentially, p < 0.01). When analyzing patients who presented to the surgical hospital after 3 days of life, there were no differences in age at repair, pre-procedural acuity, or other outcomes. Age at repair of coarctation of the aorta and acuity did not change after the start of the COVID-19 pandemic. This suggests that the safeguards in place to ensure timely diagnosis of critical heart disease were adequate during this time of disruption.
患有主动脉缩窄的新生儿是一个潜在的脆弱群体,其诊断可能受到了新冠疫情的影响。本研究的目的是评估主动脉缩窄婴儿是否存在诊断延迟,以及在疫情开始后修复前他们的病情严重程度是否更高。查询了儿科健康信息系统数据库中年龄小于三个月且接受了主动脉缩窄手术修复或姑息治疗的患者。患者被分为三个时间段:(1)新冠疫情前(2017年10月至2019年12月),(2)新冠疫情早期(2020年1月至2020年12月),以及(3)新冠疫情后期(2021年1月至2021年12月)。观察指标为修复时的年龄和术前病情严重程度。在4885例患者中,所有时间段的中位修复时间均为10天。疫情开始后,术前使用机械通气、血管升压药和体外膜肺氧合的情况并未增加。疫情开始后住院时间中位数增加,且未恢复到基线水平(依次为22天、24天和25天,p<0.01)。分析出生后3天以上到外科医院就诊的患者时,修复时的年龄、术前病情严重程度或其他观察指标没有差异。新冠疫情开始后,主动脉缩窄的修复年龄和病情严重程度没有变化。这表明在这段混乱时期,为确保及时诊断严重心脏病而采取的保障措施是足够的。