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理解与痴呆症患者生活方式干预相关的影响:系统评价方案。

Understanding the impact related to lifestyle interventions for people with dementia: A systematic review protocol.

机构信息

Schlegel-University of Waterloo Research Institute for Aging, Waterloo, Ontario, Canada.

School of Public Health Sciences, University of Waterloo, Waterloo, Ontario, Canada.

出版信息

PLoS One. 2024 Sep 26;19(9):e0310690. doi: 10.1371/journal.pone.0310690. eCollection 2024.

Abstract

There is growing evidence to suggest that lifestyle initiatives promote brain health and reduce dementia risk. However, there is comparatively limited research focused on lifestyle interventions among people living with dementia. Most recent systematic reviews of lifestyle interventions among people living with dementia centre on the impact of exercise on cognition; yet, functional abilities and quality of life are most consistently prioritized by people living with dementia, care partners, and healthcare professionals. There is insufficient evidence to inform guidelines on effective lifestyle interventions, programs, resources, and policies for people living with dementia. To address this knowledge gap, the objective of this study is to perform a systematic review to understand the impact of lifestyle interventions among people living with dementia. The specific research questions are: "What is the effectiveness of physical activity interventions on improving functional abilities and quality of life among community-dwelling people living with dementia?", "What is the effectiveness of healthy eating/nutrition on improving nutritional status or quality of life among community-dwelling people living with dementia?" and "Does the effectiveness of interventions vary depending on the components (single or multi), setting (in-home or community centre, geography), program structure, mode of delivery, dosage, and participant characteristics (sex/gender, ethno-cultural or language group, race, dementia type)?" The results from this review will inform recommendations of lifestyle interventions and their delivery among people living with dementia in the community. Trial registration: Systematic review registration PROSPERO #CRD42024509408.

摘要

越来越多的证据表明,生活方式干预措施可促进大脑健康并降低痴呆症风险。然而,针对痴呆症患者的生活方式干预措施的研究相对较少。最近针对痴呆症患者生活方式干预措施的系统评价主要集中在运动对认知的影响上;然而,功能能力和生活质量是痴呆症患者、护理伙伴和医疗保健专业人员最关注的问题。目前,尚无足够的证据为痴呆症患者的有效生活方式干预措施、方案、资源和政策提供指导。为了弥补这一知识空白,本研究的目的是进行系统评价,以了解痴呆症患者生活方式干预措施的效果。具体的研究问题是:“身体活动干预措施在改善社区居住的痴呆症患者的功能能力和生活质量方面的效果如何?”“健康饮食/营养在改善社区居住的痴呆症患者的营养状况或生活质量方面的效果如何?”以及“干预措施的效果是否因干预措施的组成部分(单一或多种)、环境(家庭或社区中心、地理位置)、方案结构、交付模式、剂量和参与者特征(性别/性别、民族文化或语言群体、种族、痴呆症类型)而异?”本综述的结果将为社区中痴呆症患者的生活方式干预措施及其实施提供建议。试验注册:系统评价注册 PROSPERO #CRD42024509408。

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