Aaron Devarajan Jebin, Warikoo Vikas, Salunke Abhijeet, Pawar Ajinkya, Kapur Kanika, Sharma Mohit, Pandya Shashank
Department of Surgical Oncology, The Gujarat Cancer & Research Institute, Ahmedabad, Gujarat India.
Indian J Surg Oncol. 2024 Sep;15(Suppl 3):418-422. doi: 10.1007/s13193-024-01989-9. Epub 2024 Jul 2.
Lipoleiomyosarcoma is a malignant tumor of both mesenchymal and smooth muscle origin. Lipoleiomyosarcoma is a very rare type of retroperitoneal sarcoma, which by itself is a rare type of soft tissue sarcoma. Lipoleiomyosarcoma is a very rare subtype of liposarcoma, which is the most common type of retroperitoneal sarcoma. To our best review of available literature, this was the first case of lipoleiomyosarcoma presenting as a massive retroperitoneal mass of size 50 × 50 × 30 cm, managed with multi-visceral R0 resection. The computed tomography of the abdomen showed a massive fat density lesion with internal soft density lesions and internal calcifications. Multivisceral resection was planned and executed and achieved R0 resection. We suggest that lipoleiomyosarcoma should be included in differential diagnosis of retroperitoneal tumors, and multi-visceral R0 resection should be considered as an option for lipoleiomyosarcoma, as these tumors have very good prognosis with R0 resection.
脂肪平滑肌肉瘤是一种起源于间叶组织和平滑肌的恶性肿瘤。脂肪平滑肌肉瘤是一种非常罕见的腹膜后肉瘤类型,而腹膜后肉瘤本身就是一种罕见的软组织肉瘤类型。脂肪平滑肌肉瘤是脂肪肉瘤中一种非常罕见的亚型,脂肪肉瘤是腹膜后肉瘤最常见的类型。据我们对现有文献的最佳检索,这是首例表现为大小为50×50×30cm的巨大腹膜后肿块的脂肪平滑肌肉瘤病例,通过多脏器R0切除进行治疗。腹部计算机断层扫描显示一个巨大的脂肪密度病变,内部有软组织密度病变和内部钙化。计划并实施了多脏器切除,实现了R0切除。我们建议脂肪平滑肌肉瘤应纳入腹膜后肿瘤的鉴别诊断,对于脂肪平滑肌肉瘤应考虑多脏器R0切除作为一种选择,因为这些肿瘤行R0切除预后非常好。