Ghodsian Diba, D'Jesús Sofía, Sánchez-Labrador Luis, Cobo-Vázquez Carlos Manuel, Cortés-Bretón Brinkmann Jorge, Martínez-González José María, Meniz-García Cristina
Department of Dental Clinical Specialties, Faculty of Dentistry, Complutense University of Madrid, 28040 Madrid, Spain.
Biomimetics (Basel). 2024 Aug 29;9(9):518. doi: 10.3390/biomimetics9090518.
The aim of this systematic review was to determine whether autogenous tooth grafting material (ATGM) is as safe and effective as other bone substitutes used for maxillary sinus augmentation procedures, evaluating histomorphometric and/or histological data, implant primary stability, associated complications and radiographic bone height measurements. An automated electronic search was conducted using four databases (Medline/PubMed, Scopus, Web of Science and Cochrane Library), supplemented by a manual search, to identify clinical human studies using particulate ATGM for the aforementioned procedure. The included studies had a sample size of at least four patients and were published before 31st July 2024. The Newcastle-Ottawa scale (NOS) and Joanna Briggs Institute (JBI) Critical Appraisal Checklist were used to assess the risk of bias in cohort studies and case series, respectively. Seven studies were included in the descriptive analysis, obtaining 128 participants (46.8% only treated with ATGM) and 192 placed implants. Due to the heterogeneity of the studies, meta-analysis could not be performed. The authors concluded that ATGM appears to be a feasible and safe alternative for maxillary sinus augmentation procedures. These results should be interpreted with caution due to the limited amount of scientific evidence on this topic and the heterogeneity between the included studies.
本系统评价的目的是确定自体牙移植材料(ATGM)在上颌窦提升术中是否与其他骨替代材料一样安全有效,评估组织形态计量学和/或组织学数据、种植体初期稳定性、相关并发症及影像学骨高度测量值。通过使用四个数据库(Medline/PubMed、Scopus、Web of Science和Cochrane图书馆)进行自动电子检索,并辅以手工检索,以识别使用颗粒状ATGM进行上述手术的临床人体研究。纳入的研究样本量至少为4例患者,且发表于2024年7月31日之前。分别使用纽卡斯尔-渥太华量表(NOS)和乔安娜·布里格斯研究所(JBI)批判性评价清单来评估队列研究和病例系列中的偏倚风险。七项研究纳入描述性分析,共获得128名参与者(46.8%仅接受ATGM治疗)和192枚植入种植体。由于研究的异质性,无法进行荟萃分析。作者得出结论,ATGM似乎是上颌窦提升术的一种可行且安全的替代方法。鉴于关于该主题的科学证据有限且纳入研究之间存在异质性,这些结果应谨慎解读。