采用CRISPR技术的新源MB-1减轻与痤疮相关病毒（噬菌体）的影响——病例报告
NeoGenesis MB-1 with CRISPR Technology Reduces the Effects of the Viruses (Phages) Associated with Acne - Case Report.
作者信息
Maguire Greg, McGee Steven T
机构信息
California Physiological Society and Neogenesis, Inc.
出版信息
Integr Med (Encinitas). 2024 Sep;23(4):34-38.
We present a case of acne successfully treated with a topical spray containing live bacteria. The live bacteria used in the spray contain CRISPR, and adaptive immune system in the bacteria that are used to disable viral replication. Because acne skin contains bacteria in the microbiome where a shift toward non-CRISPR bacteria occurs, these bacteria are susceptible to bacteriophage infection and lysogeny. Normalizing the bacterial microbiome to one containing more CRISPR-containing bacteria renormalizes the microbiome by killing inflammation-causing bacteriophage infecting the non-CRISPR bacteria associated with acne.
我们展示了一例使用含有活细菌的外用喷雾成功治疗痤疮的病例。喷雾中使用的活细菌含有CRISPR，这是细菌中用于阻止病毒复制的一种适应性免疫系统。由于痤疮皮肤的微生物群中含有细菌，且会出现向非CRISPR细菌转变的情况，这些细菌易受噬菌体感染和溶原作用影响。将细菌微生物群恢复到含有更多含CRISPR细菌的状态，通过杀死感染与痤疮相关的非CRISPR细菌的致炎噬菌体，使微生物群恢复正常。
Zotero 插件