Ruan Dan, Sun Long
Department of Nuclear Medicine, Zhongshan Hospital, Fudan University (Xiamen Branch), Xiamen, China.
Department of Nuclear Medicine and Minnan PET Center, Xiamen Cancer Hospital, The First Affiliated Hospital of Xiamen University, Xiamen, China.
Front Nucl Med. 2021 Dec 14;1:780485. doi: 10.3389/fnume.2021.780485. eCollection 2021.
Pleuropulmonary blastoma (PPB) is a rare invasive primary malignancy in the thoracic cavity that occurs mainly in infants and children. It is often misdiagnosed and not treated correctly and promptly due to the lack of specificity of clinical symptoms and conventional imaging presentations. We report a 2.5-year-old boy who underwent X-ray chest radiography, chest CT, and F-FDG PET/CT. PET/CT images demonstrated a sizeable cystic-solid mass with heterogeneous increased glucose metabolism in the left thoracic cavity. The diagnosis of PPB (type II) was finally confirmed by a CT-guided puncture biopsy of the active tumor tissue. This case highlights the critical role of F-FDG PET/CT in the diagnosis of PPB in children.
肺胚细胞瘤(PPB)是一种罕见的胸腔原发性侵袭性恶性肿瘤,主要发生于婴幼儿和儿童。由于临床症状和传统影像学表现缺乏特异性,PPB常被误诊,且未得到正确及时的治疗。我们报告一名2.5岁男孩,其接受了胸部X线摄影、胸部CT及F-FDG PET/CT检查。PET/CT图像显示左胸腔有一个较大的囊实性肿块,葡萄糖代谢不均匀增高。最终通过对活性肿瘤组织进行CT引导下穿刺活检确诊为II型PPB。该病例突出了F-FDG PET/CT在儿童PPB诊断中的关键作用。