Tittle Victoria, Day Sara Louise, Tostevin Anna, Kelly Adrian M, Spate Jonathan, Burns Fiona, Gibbs Jo, Howarth Alison, Sullivan Ann
Sexual Health and HIV, Chelsea and Westminster Hospital NHS Foundation Trust, London, UK
Sexual Health and HIV, Chelsea and Westminster Healthcare NHS Trust, London, UK.
Sex Transm Infect. 2025 Jan 29;101(1):41-48. doi: 10.1136/sextrans-2024-056232.
Since 2018, Sexual Health London (SHL) has provided remote sexually transmitted infection (STI) testing services to London residents over 16 years of age. SHL was an asymptomatic screening service. In 2020, SHL widened access to non-urgent symptomatic testing. We undertook a 4-year evaluation on the uptake of SHL's online testing pathway and outcomes, including the association of positive chlamydia and gonorrhoea nucleic acid amplification test (NAAT) outcomes with user demographics and user utility.
This is a retrospective data analysis of routine SHL clinical data from 8 January 2018 to 31 March 2022 of all STI test kit orders, focusing on HIV, chlamydia and gonorrhoea outcomes. Descriptive analysis on uptake of each stage of SHL's clinical care pathway is provided, including HIV testing outcomes. Binary logistic regression was used to examine the association between SHL user-completed online consultation information, SHL uptake and chlamydia and gonorrhoea NAAT results (negative or positive).
During the evaluation period, there were 1 476 187 orders made by 670 293 unique users. The return rate for chlamydia and gonorrhoea NAATs was 79.5% and 67.6% for HIV blood samples. The positivity rate from sufficient samples was 4.5% for chlamydia, 1.6% for gonorrhoea and 0.3% reactivity for HIV. There were increased odds of a positive chlamydia and gonorrhoea NAAT result in non-cisgender women, those with a high number of STI orders, non-UK born and those who collected an STI test kit from a clinic-based service.
To date, this is the largest number of orders in an evaluation of online postal sexual health infection testing in the UK, and highest return rate of samples, suggesting acceptability of SHL for STI testing. Positivity rates for chlamydia and gonorrhoea NAAT tests are lower than national figures, which may reflect asymptomatic screening prior to 2020 and testing of non-urgent symptoms since 2020.
自2018年以来,伦敦性健康组织(SHL)为16岁以上的伦敦居民提供远程性传播感染(STI)检测服务。SHL是一项无症状筛查服务。2020年,SHL扩大了非紧急症状检测的范围。我们对SHL在线检测途径的使用情况和结果进行了为期4年的评估,包括衣原体和淋病核酸扩增检测(NAAT)阳性结果与用户人口统计学特征和用户效用之间的关联。
这是一项对2018年1月8日至2022年3月31日期间SHL所有性传播感染检测试剂盒订单的常规临床数据进行的回顾性数据分析,重点关注艾滋病毒、衣原体和淋病的检测结果。提供了对SHL临床护理途径各阶段使用情况的描述性分析,包括艾滋病毒检测结果。采用二元逻辑回归分析SHL用户完成的在线咨询信息、SHL使用情况与衣原体和淋病NAAT结果(阴性或阳性)之间的关联。
在评估期间,670293名独特用户共下单1476187次。衣原体和淋病NAAT的样本回收率分别为79.5%,艾滋病毒血样的回收率为67.6%。足够样本的阳性率分别为:衣原体4.5%,淋病1.6%,艾滋病毒反应性为0.3%。非顺性别女性、性传播感染订单数量多的人、非英国出生的人以及从门诊服务处领取性传播感染检测试剂盒的人,衣原体和淋病NAAT结果呈阳性的几率增加。
迄今为止,这是英国在线邮寄性健康感染检测评估中订单数量最多、样本回收率最高的一次,表明SHL的性传播感染检测具有可接受性。衣原体和淋病NAAT检测的阳性率低于全国数据,这可能反映了2020年之前的无症状筛查以及2020年以来对非紧急症状的检测。