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美国 2011-2014 年 NHANES 横断面调查中 40 岁及以上美国老年人的体型指数与认知障碍的关系。

Association between a body shape index and cognitive impairment among US older adults aged 40 years and above from a cross-sectional survey of the NHANES 2011-2014.

机构信息

Department of Anesthesiology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

出版信息

Front Endocrinol (Lausanne). 2024 Sep 23;15:1411701. doi: 10.3389/fendo.2024.1411701. eCollection 2024.

Abstract

PURPOSE

This research aimed to assess the correlation between the Adjusted Body Shape Index (ABSI) and the presence of abdominal aortic calcification (AAC) among middle-aged and older American adults.

METHODS

Employing a cross-sectional design, this study analyzed data from the 2013-2014 National Health and Nutrition Examination Survey (NHANES), focusing on 3077 participants aged 40 and above. AAC detection was conducted using dual-energy X-ray absorptiometry (DXA). ABSI was determined based on waist circumference (WC), weight, and height data. The association between ABSI and AAC was examined through multiple linear regression, smoothed curve analysis, threshold effect evaluation, subgroup analysis, and interaction testing.

RESULTS

The study encompassed 3077 individuals aged 40 and above. Findings indicated a noteworthy positive relationship between ABSI and AAC when adjusting various covariates. Analysis of threshold effects identified a K-point at 0.0908, showing no significant effect to its left but a significant effect to its right. Further, subgroup and interaction analyses highlighted the ABSI-AAC connection specifically within different age groups and among individuals with diabetes.

CONCLUSION

Higher ABSI was correlated with higher AAC score.

摘要

目的

本研究旨在评估调整体脂指数(ABSI)与中老年美国成年人腹主动脉钙化(AAC)之间的相关性。

方法

本研究采用横断面设计,分析了 2013-2014 年全国健康和营养调查(NHANES)的数据,研究对象为 3077 名年龄在 40 岁及以上的参与者。使用双能 X 射线吸收法(DXA)检测 AAC。根据腰围(WC)、体重和身高数据确定 ABSI。通过多元线性回归、平滑曲线分析、阈值效应评估、亚组分析和交互检验来研究 ABSI 与 AAC 之间的关系。

结果

本研究共纳入 3077 名年龄在 40 岁及以上的个体。结果表明,在调整了各种协变量后,ABSI 与 AAC 之间存在显著的正相关关系。阈值效应分析确定了 K 点为 0.0908,表明其左侧无显著影响,右侧有显著影响。此外,亚组和交互分析突出了 ABSI-AAC 之间的关系,特别是在不同年龄组和糖尿病患者中。

结论

较高的 ABSI 与较高的 AAC 评分相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9cef/11456444/123f1d7b8538/fendo-15-1411701-g001.jpg

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