Institute of Microbiology, Government College University Faisalabad, Faisalabad, Pakistan.
National Institute of Health, Islamabad, Pakistan.
Global Health. 2024 Oct 17;20(1):73. doi: 10.1186/s12992-024-01046-8.
Antimicrobial resistance (AMR) poses a significant global health threat, primarily stemming from its misuse and overuse in both veterinary and public healthcare systems. The consequences of AMR are severe, leading to more severe infections, increased health protection costs, prolonged hospital stays, unresponsive treatments, and elevated fatality rates. The impact of AMR is direct and far-reaching, particularly affecting the Sustainable Development Goals (SDGs), underscoring the urgency for concerted global actions to achieve these objectives. Disproportionately affecting underprivileged populations, AMR compounds their vulnerabilities, pushing them further into poverty. Moreover, AMR has ramifications for food production, jeopardizing sustainable agriculture and diminishing the livelihoods of farmers. The emergence of antibiotic-resistant bacteria in underprivileged areas heightens the risk of complications and mortality. Climate change further contributes to AMR, as evidenced by increased instances of foodborne salmonellosis and the development of antibiotic resistance, resulting in substantial healthcare costs. Effectively addressing AMR demands collaboration among governments, entrepreneurs, and the public sector to establish institutions and policies across all regulatory levels. Expanding SDG 17, which focuses on partnerships for sustainable development, would facilitate global antimicrobial stewardship initiatives, technology transfer, surveillance systems, and investment in vaccine and drug research. The World Bank's SDG database, tracking progress towards sustainable development, reveals a concerning picture with only a 15% success rate till 2023 and 48% showing deviation, underscoring a global gap exacerbated by the COVID-19 pandemic. Tackling AMR's global impact necessitates international cooperation, robust monitoring, and evaluation methods. The five priorities outlined guide SDG implementation, while impoverished countries must address specific challenges in their implementation efforts. Addressing AMR and its impact on the SDGs is a multifaceted challenge that demands comprehensive and collaborative solutions on a global scale.
抗微生物药物耐药性(AMR)对全球健康构成重大威胁,主要源于兽医和公共卫生保健系统中对其的不适当和过度使用。AMR 的后果严重,导致感染更严重、卫生保健费用增加、住院时间延长、治疗效果不佳和死亡率上升。AMR 的影响是直接且深远的,特别是对可持续发展目标(SDGs)产生影响,突显了全球采取协调一致行动实现这些目标的紧迫性。抗微生物药物耐药性不成比例地影响弱势群体,使他们更加脆弱,陷入贫困。此外,AMR 对粮食生产产生影响,危及可持续农业并减少农民的生计。贫困地区出现具有抗药性的细菌,增加了并发症和死亡率的风险。气候变化进一步加剧了 AMR,例如食源性沙门氏菌病的增加和抗生素耐药性的发展,导致医疗保健费用大幅增加。有效应对 AMR 需要政府、企业家和公共部门之间的合作,在所有监管层面建立机构和政策。扩大重点关注可持续发展伙伴关系的可持续发展目标 17,将促进全球抗菌药物管理举措、技术转让、监测系统以及在疫苗和药物研究方面的投资。世界银行的可持续发展目标数据库显示,到 2023 年,可持续发展的进展仅有 15%的成功率,48%的目标显示偏差,突显了由 COVID-19 大流行加剧的全球差距。应对 AMR 的全球影响需要国际合作、强有力的监测和评估方法。概述的五个优先事项指导可持续发展目标的实施,而贫困国家必须在实施努力中应对具体挑战。应对 AMR 及其对可持续发展目标的影响是一个多方面的挑战,需要在全球范围内采取全面和协作的解决方案。