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[头颈癌:与临床及病理检查结果相关的治疗选择]

[Head and neck cancer: choice of treatment in relation to clinical and pathological findings].

作者信息

Ono I

出版信息

Gan To Kagaku Ryoho. 1986 Jan;13(1):18-23.

PMID:3942398
Abstract

There are several organs in the head and neck region, and cancers arising in this region show a variety of histological findings. Therefore, the first choice of treatment for head and neck cancer should be decided according to sites of origin, clinical staging and pathological findings. Furthermore, the head and neck region plays very important roles in speaking, eating, and esthetic functions. The principles of treatment for head and neck cancer are as follows. As regards carcinoma of the larynx and oral cavity, radiotherapy is usually adopted when the carcinoma is small and limited, and surgical treatment is recommended in cases of rather advanced carcinoma. In the treatment of carcinoma of the nasopharynx, radiotherapy is undoubtedly the first choice of treatment and chemotherapy is combined in advanced cases. In the case of carcinoma of the methopharynx, surgical treatment is advisable for well differentiated squamous cell carcinoma and radiotherapy for poorly differentiated squamous cell carcinoma. For carcinoma of the hypopharynx, surgical treatment is advisable except for T1 cases of the pyriform sinus. Combination of radiotherapy, arterial chemotherapy and limited surgery is generally accepted as the method of treatment for maxillary sinus carcinoma.

摘要

头颈部区域有多个器官,该区域发生的癌症呈现出多种组织学表现。因此,头颈癌的首选治疗方法应根据起源部位、临床分期和病理结果来决定。此外,头颈部区域在说话、进食和美学功能方面发挥着非常重要的作用。头颈癌的治疗原则如下。对于喉癌和口腔癌,当癌症较小且局限时通常采用放疗,而对于进展期癌症则建议进行手术治疗。在鼻咽癌的治疗中,放疗无疑是首选治疗方法,晚期病例则联合化疗。对于下咽癌,高分化鳞状细胞癌宜采用手术治疗,低分化鳞状细胞癌宜采用放疗。对于下咽癌,除梨状窝T1期病例外,手术治疗为宜。放疗、动脉化疗和有限手术相结合通常被认为是上颌窦癌的治疗方法。

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