Feder Kenneth A, Li Yuzhong, Burke Kathryn N, Byrne Lauren, Desai Isha K, Saloner Brendan, Krawczyk Noa
Department of Mental Health, Johns Hopkins University Bloomberg School of Public Health, 615 N Wolfe St, Baltimore, MD 21205, United States of America.
New York University Global School of Public Health, Johns Hopkins University Bloomberg School of Public Health, 615 N Wolfe St, Baltimore, MD 21205, United States of America.
J Subst Use Addict Treat. 2025 Jan;168:209545. doi: 10.1016/j.josat.2024.209545. Epub 2024 Oct 21.
Most patients in specialty drug treatment programs that are not federally licensed Opioid Treatment Programs (OTPs) programs do not receive medications for opioid use disorder (MOUD).
We linked results from a survey of non-OTP treatment program directors in New Jersey (n = 81) to statewide administrative records of admissions for opioid use to those programs between July 2021-June 2022. Using multi-level regression, we examined the association of three types of factors with planned MOUD use: program survey responses, client-level factors, and program-level client characteristic mix.
Of 9583 opioid treatment admissions in non-OTP settings, 41 % included treatment plans involving MOUD. Programs where directors reported staff concerns about buprenorphine's efficacy or diversion had a lower proportion of clients with planned MOUD, as did programs reporting too little physical space to prescribe. Being self-referred to treatment, unemployed and not looking for work, aged 30-49, heroin use (vs. prescription opioid use), and stimulant use in addition to opioids, were positively associated with planned MOUD; while non-Medicaid insurance, and Black and Hispanic race/ethnicity, were negatively associated with planned MOUD. Clients were more likely to have planned MOUD if their programs had a higher proportion of clients aged 30 or older, heroin as primary "drug of abuse," stimulant use, and not working but actively looking for work.
Findings suggest addressing program staff attitudes toward buprenorphine could help increase planned MOUD. There is also a need to improve access for clients with non-Medicaid insurance, address within-program race and ethnic disparities, and address employment-related barriers to medication.
在非联邦许可的阿片类药物治疗项目(OTP)的专科药物治疗项目中,大多数患者未接受阿片类药物使用障碍(MOUD)的药物治疗。
我们将对新泽西州非OTP治疗项目主任的调查结果(n = 81)与2021年7月至2022年6月期间该州这些项目的阿片类药物使用入院管理记录相联系。使用多层次回归分析,我们研究了三种类型的因素与计划使用MOUD之间的关联:项目调查回复、客户层面因素以及项目层面的客户特征组合。
在非OTP环境下的9583例阿片类药物治疗入院病例中,41%的治疗计划涉及MOUD。主任报告工作人员对丁丙诺啡的疗效或转移问题存在担忧的项目,其计划使用MOUD的客户比例较低,报告没有足够物理空间进行处方开具的项目也是如此。自我转诊接受治疗、失业且未在找工作、年龄在30 - 49岁、使用海洛因(与使用处方阿片类药物相比)以及除阿片类药物外还使用兴奋剂,与计划使用MOUD呈正相关;而非医疗补助保险以及黑人与西班牙裔种族/族裔与计划使用MOUD呈负相关。如果项目中30岁及以上客户、以海洛因为主要“滥用药物”、使用兴奋剂且未工作但积极找工作的客户比例较高,那么客户更有可能有计划使用MOUD。
研究结果表明,解决项目工作人员对丁丙诺啡的态度问题可能有助于增加计划使用MOUD的情况。还需要改善非医疗补助保险客户的获取途径,解决项目内的种族和族裔差异问题,并消除与就业相关的药物治疗障碍。