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俱乐部药物与精神科结局:来自西班牙的描述性病例系列

Club Drugs and Psychiatric Outcomes: A Descriptive Case Series from Spain.

作者信息

Montemitro Chiara, Mosca Alessio, Chiappini Stefania, Miuli Andrea, Schifano Fabrizio, Montano Maria Josè Gordillo, Villar Cristina Merino Del, Allegretti Rita, Marrangone Carlotta, Di Petta Gilberto, De Berardis Domenico, Pettorruso Mauro, Martinotti Giovanni

机构信息

Department of Neurosciences, Imaging and Clinical Sciences, G. D'Annunzio University of Chieti, 66100 Chieti, Italy.

School of Medicine, UniCamillus International Medical School University, Via di S. Alessandro 8, 00131 Rome, Italy.

出版信息

Pharmaceuticals (Basel). 2024 Oct 17;17(10):1387. doi: 10.3390/ph17101387.

Abstract

BACKGROUND

illegal drugs significantly contribute to global health issues, with health complications often occurring not only in regular users with Substance Use Disorders (SUDs) but also in first-time and occasional users.

METHODS

this study examines five clinical cases from a public hospital in Ibiza, Spain, where patients presented with acute psychiatric symptoms due to recreational drug use.

RESULTS

Contrary to previous studies on SUDs, our patients typically had higher education levels and stable employment. Most of them used multiple substances, with cannabis, cocaine, and alcohol being the most frequently used. There was also a common occurrence of consuming drugs with uncertain contents. Upon admission, typical symptoms included aggression, hallucinations, mood swings, and disorientation in time and space.

CONCLUSIONS

Our findings underscore the significant mental health risks posed by illicit drugs, even for individuals with no prior psychiatric history. Factors like the drug's potency, frequency and amount of use, past mental health issues, personality traits, and previous traumatic experiences might influence the onset of these symptoms.

摘要

背景

非法药物对全球健康问题有重大影响,健康并发症不仅经常出现在患有物质使用障碍(SUDs)的常规使用者中,也出现在初次使用者和偶尔使用者身上。

方法

本研究调查了西班牙伊维萨岛一家公立医院的五个临床病例,这些患者因娱乐性药物使用而出现急性精神症状。

结果

与先前关于物质使用障碍的研究相反,我们的患者通常具有较高的教育水平和稳定的工作。他们中的大多数人使用多种物质,大麻、可卡因和酒精是最常用的。还经常出现摄入成分不明的药物的情况。入院时,典型症状包括攻击性、幻觉、情绪波动以及时间和空间定向障碍。

结论

我们的研究结果强调了非法药物对心理健康构成的重大风险,即使对于没有精神病史的个体也是如此。药物效力、使用频率和量、过去的心理健康问题、人格特质以及先前的创伤经历等因素可能会影响这些症状的发作。

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