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老年人跌倒预防策略的成本效益:一项实时系统综述的方案。

Cost-effectiveness of falls prevention strategies for older adults: protocol for a living systematic review.

机构信息

Faculty of Management, The University of British Columbia Okanagan, Kelowna, British Columbia, Canada

Faculty of Management, The University of British Columbia Okanagan, Kelowna, British Columbia, Canada.

出版信息

BMJ Open. 2024 Nov 5;14(11):e088536. doi: 10.1136/bmjopen-2024-088536.

Abstract

INTRODUCTION

One-third of adults aged 65+ fall annually. Injuries from falls can be devastating for individuals and account for 1.5% of annual healthcare spending. With the growing ageing population, falls place increased strain on scarce health resources. Prevention strategies that target individuals at high risk for falls demonstrate the best value for money; however, limited efficiency (ie, cost-effectiveness) information for fall prevention interventions hinders the implementation of effective falls prevention programmes. Living systematic reviews provide a timely up-to-date evidence-based resource to inform clinical guidelines and health policy decisions. This protocol details the methodology for a living systematic review of the efficiency (ie, cost-effectiveness) of fall prevention interventions for older adults in three settings: community-dwelling, aged care and hospitals.

METHODS AND ANALYSIS

This protocol used the reporting guidelines from the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Protocol. Peer-reviewed economic evaluations of controlled clinical trials or health state models will be included. Reports will be obtained through monthly systematic searches of CENTRAL (Ovid), CINAHL (EBSCO), Embase (Ovid), MEDLINE (Ovid), SCOPUS (Elsevier) and Web of Science (Clarivate) alongside snowballing and handsearching EconLit and the Tufts Cost Effectivness Analysis Registry. Screening, data extraction, quality assessment and risk of bias will be assessed by multiple reviewers. The primary outcomes will be the incremental cost-effectiveness (ie, incremental cost per fall prevented), incremental cost-utility (ie, incremental cost per quality-adjusted life year gained) or cost-benefit ratio. Additional outcomes will include falls and cost-related measures. All economic outcomes will be reported in a common year and currency. Results will be reported as a narrative synthesis; meta-analysis will be considered based on data quality, suitability and availability.

ETHICS AND DISSEMINATION

Ethical approval is not required as primary human data will not be collected. Results will be disseminated through peer-reviewed publications and a dedicated website.

PROSPERO REGISTRATION NUMBER

CRD42024532485.

摘要

简介

三分之一的 65 岁以上成年人每年都会跌倒。跌倒造成的伤害对个人来说可能是毁灭性的,占每年医疗保健支出的 1.5%。随着人口老龄化的增长,跌倒给稀缺的卫生资源带来了更大的压力。针对高跌倒风险人群的预防策略具有最佳的性价比;然而,有限的跌倒预防干预措施的效率(即成本效益)信息阻碍了有效的跌倒预防计划的实施。实时系统评价为临床指南和卫生政策决策提供了及时的基于证据的资源。本方案详细说明了对社区居住、老年护理和医院三种环境中老年人跌倒预防干预措施的效率(即成本效益)进行实时系统评价的方法。

方法和分析

本方案使用了系统评价和荟萃分析报告规范。将纳入经过同行评审的、针对对照临床试验或健康状态模型的经济评价。报告将通过每月对 CENTRAL(Ovid)、CINAHL(EBSCO)、Embase(Ovid)、MEDLINE(Ovid)、SCOPUS(Elsevier)和 Web of Science(Clarivate)进行系统搜索以及滚雪球式搜索和手工搜索 EconLit 和 Tufts 成本效益分析登记处获得。由多名评审员进行筛选、数据提取、质量评估和偏倚风险评估。主要结果将是增量成本效益(即每预防一次跌倒的增量成本)、增量成本效用(即每获得一个质量调整生命年的增量成本)或成本效益比。其他结果将包括跌倒和成本相关的措施。所有经济结果将以通用年和货币报告。结果将以叙述性综合报告;根据数据质量、适用性和可用性,将考虑进行荟萃分析。

伦理和传播

由于不会收集主要的人类数据,因此不需要伦理批准。结果将通过同行评审的出版物和专门的网站进行传播。

PROSPERO 注册号:CRD42024532485。

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