Ntanika Anna, Tzortzopoulou Adelais, Argyri Ioanna, Dendi Artemis, Achilleos Orthodoxos
2nd Department of Pediatric Surgery, General Children's Hospital of Athens "P. & A. Kyriakou", Athens, Greece.
2nd Department of Pediatric Surgery, General Children's Hospital of Athens "P. & A. Kyriakou", Athens, Greece.
Int J Surg Case Rep. 2024 Dec;125:110550. doi: 10.1016/j.ijscr.2024.110550. Epub 2024 Nov 3.
Necrotizing fasciitis (NF) is a rare life-threatening medical and surgical emergency. We present a case of a pediatric patient diagnosed with necrotizing fasciitis in the inguinal area which required debridement and post-operative management of the residual wound using a combination of wound closure techniques.
A 10-months-old girl with a history of Food-protein induced enterocolitis syndrome (FPIES) presented with septic shock and ulcerative lesions of the inguinal area. She was admitted to the Intensive Care Unit (ICU) of our hospital, antibiotic treatment was administered and a diverting colostomy was performed. Serial surgical debridement of the affected tissues resulted in an extensive tissue deficit. Management of the residual skin and soft tissues deficit included application of Negative Pressure Wound Therapy (NPWT) with Vacuum-Assisted Closure (VAC) and was followed by Oasis® extracellular matrix (ECM) graft placement. After 65 days of hospitalization, the wound surface was completely epithelialized.
A challenging aspect of NF management is the closure of the residual skin and soft tissue deficit after surgical debridement. Considering the patient's characteristics, a less invasive reconstructive technique was sought. Application of NPWT followed by ECM graft placement are two effective options that can be combined in different stages of wound healing.
The management of the residual wound after surgical debridement of the affected tissue in NF requires a patient - specific approach and constant reevaluation of the management plan. NPWT and ECM graft placement can significantly contribute to wound closure and epithelization of the residual deficit in children.
坏死性筋膜炎(NF)是一种罕见的危及生命的内科和外科急症。我们报告一例腹股沟区诊断为坏死性筋膜炎的儿科患者,该患者需要进行清创,并使用多种伤口闭合技术对残余伤口进行术后处理。
一名10个月大、有食物蛋白诱导的小肠结肠炎综合征(FPIES)病史的女孩,出现感染性休克和腹股沟区溃疡性病变。她被收治入我院重症监护病房(ICU),接受了抗生素治疗并进行了转流性结肠造口术。对受影响组织进行系列手术清创导致广泛的组织缺损。对残余皮肤和软组织缺损的处理包括应用带有真空辅助闭合(VAC)的负压伤口治疗(NPWT),随后植入Oasis®细胞外基质(ECM)移植物。住院65天后,创面完全上皮化。
NF治疗中一个具有挑战性的方面是手术清创后残余皮肤和软组织缺损的闭合。考虑到患者的特点,寻求一种侵入性较小的重建技术。应用NPWT随后植入ECM移植物是两种有效的选择,可在伤口愈合的不同阶段联合使用。
NF患者受影响组织手术清创后残余伤口的处理需要针对患者的个体化方法,并不断重新评估治疗方案。NPWT和ECM移植物植入可显著促进儿童残余缺损伤口的闭合和上皮化。