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打破障碍:为何将男孩和男性纳入 HPV 预防工作至关重要。

Breaking barriers: why including boys and men is key to HPV prevention.

机构信息

Health Promotion Unit, KwaZulu-Natal Department of Health, Pietermaritzburg, South Africa.

Discipline of Psychology, School of Applied Human Sciences, Howard College, University of KwaZulu-Natal, Durban, South Africa.

出版信息

BMC Med. 2024 Nov 8;22(1):525. doi: 10.1186/s12916-024-03701-8.

DOI:10.1186/s12916-024-03701-8
PMID:39516809
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11549739/
Abstract

Despite the common belief that human papillomavirus (HPV) primarily affects women, it is imperative to recognize and address the impact of HPV on boys and men. Overlooking the health implications for males is a notable gap, as efforts have predominantly focused on preventing HPV-related infections in women. This commentary aims to emphasize the importance of HPV awareness and vaccination for boys and men by highlighting the prevalence and consequences of HPV infection, elaborating on the associated health risks, elucidating the benefits of vaccination, and urging readers to recognize the necessity of protecting males from HPV. In addition, the increase in HPV-related cancers in men underscores the urgent need for increased awareness and vaccination. Although specific testing for HPV in men is not available, the inclusion of men and boys in gender-neutral vaccination programs can help reduce the harmful effects of this virus in both genders.

摘要

尽管人们普遍认为人乳头瘤病毒(HPV)主要影响女性,但必须认识到 HPV 对男孩和男性的影响,并加以解决。忽视男性的健康影响是一个显著的差距,因为努力主要集中在预防女性 HPV 相关感染上。本评论旨在强调 HPV 意识和疫苗接种对男孩和男性的重要性,强调 HPV 感染的普遍性和后果,详细阐述相关的健康风险,阐明疫苗接种的益处,并敦促读者认识到保护男性免受 HPV 感染的必要性。此外,男性 HPV 相关癌症的增加突显出提高认识和接种疫苗的紧迫性。尽管目前尚无针对男性 HPV 的特定检测方法,但将男性和男孩纳入性别中立的疫苗接种计划可以帮助减少这种病毒对两性的有害影响。

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Cell Host Microbe. 2023 Nov 8;31(11):1921-1929.e3. doi: 10.1016/j.chom.2023.10.001.
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J Infect Dis. 2024 Mar 14;229(3):691-706. doi: 10.1093/infdis/jiad450.
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HPV-related diseases in male patients: an underestimated conundrum.男性患者的 HPV 相关疾病:一个被低估的难题。
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Global and regional estimates of genital human papillomavirus prevalence among men: a systematic review and meta-analysis.全球和地区男性人群生殖器人乳头瘤病毒感染率的估计:系统评价和荟萃分析。
Lancet Glob Health. 2023 Sep;11(9):e1345-e1362. doi: 10.1016/S2214-109X(23)00305-4.
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Recent Developments in Human Papillomavirus (HPV) Vaccinology.人乳头瘤病毒(HPV)疫苗学的最新进展。
Viruses. 2023 Jun 26;15(7):1440. doi: 10.3390/v15071440.
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