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黏液样成分增加导致快速生长的黏液样孤立性纤维瘤:一例报告

Myxoid solitary fibrous tumor with rapid growth due to increased mucinous components: a case report.

作者信息

Kondo Kaoru, Shiotani Toshio, Furukawa Shinichi, Watanabe Mototsugu, Kataoka Kazuhiko

机构信息

Department of Thoracic Surgery, National Hospital Organization Iwakuni Clinical Center, 1-1-1 Atago-Machi, Iwakuni-City, Yamaguchi, 740-8510, Japan.

出版信息

Gen Thorac Cardiovasc Surg Cases. 2023 Aug 1;2(1):67. doi: 10.1186/s44215-023-00081-y.

Abstract

BACKGROUND

Myxoid solitary fibrous tumors are defined as solitary fibrous tumors with ≥ 50% mucinous components. As they are a rare type of pleural tumor, no reports on their rapid growth before surgery exist.

CASE PRESENTATION

Herein, we report the case of a 63-year-old male patient with a myxoid solitary fibrous tumor. The tumor had grown rapidly from 27 to 50 mm over 6 months, and a contrast-enhancing area was observed in approximately one-quarter of the tumor on computed tomography. The tumor was located in the parietal pleura at the ventral part of the left fourth intercostal space without adhesion or invasion into surrounding organs. It was completely resected via video-assisted thoracic surgery. Based on histopathological and immunohistochemical findings, the tumor was identified as a myxoid solitary fibrous tumor. The patient was discharged on postoperative day 2 and has had recurrence-free survival for 6 months postoperatively.

CONCLUSIONS

To the best of our knowledge, this is the first case to report the rapid growth of myxoid solitary fibrous tumor despite its predominantly benign nature. Myxoid solitary fibrous tumors should be considered in the differential diagnosis of rapidly growing preoperative tumors.

摘要

背景

黏液样孤立性纤维瘤被定义为黏液成分≥50%的孤立性纤维瘤。由于它们是一种罕见的胸膜肿瘤,术前关于其快速生长的报道尚无。

病例报告

在此,我们报告一例63岁男性黏液样孤立性纤维瘤患者。该肿瘤在6个月内从27毫米迅速生长至50毫米,计算机断层扫描显示肿瘤约四分之一区域有强化。肿瘤位于左第四肋间间隙腹侧的壁层胸膜,未与周围器官粘连或侵犯周围器官。通过电视辅助胸腔镜手术将其完整切除。根据组织病理学和免疫组化结果,该肿瘤被确诊为黏液样孤立性纤维瘤。患者术后第2天出院,术后6个月无复发存活。

结论

据我们所知,这是首例报告黏液样孤立性纤维瘤尽管本质上主要为良性但仍快速生长的病例。在术前快速生长肿瘤的鉴别诊断中应考虑黏液样孤立性纤维瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8520/11533597/9959455f7116/44215_2023_81_Fig1_HTML.jpg

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